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Sato D, Clancy CE, Bers DM. Dynamics of sodium current mediated early afterdepolarizations. Heliyon. 2017;3(9):e00388doi: 10.1016/j.heliyon.2017.e00388.
Sato, D., Clancy, C. E., & Bers, D. M. (2017). Dynamics of sodium current mediated early afterdepolarizations. Heliyon, 3(9), e00388. https://doi.org/10.1016/j.heliyon.2017.e00388
Sato, Daisuke, et al. "Dynamics of sodium current mediated early afterdepolarizations." Heliyon vol. 3,9 (2017): e00388. doi: https://doi.org/10.1016/j.heliyon.2017.e00388
Sato D, Clancy CE, Bers DM. Dynamics of sodium current mediated early afterdepolarizations. Heliyon. 2017 Sep 06;3(9):e00388. doi: 10.1016/j.heliyon.2017.e00388. eCollection 2017 Sep. PMID: 28924617; PMCID: PMC5591396.
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Heliyon. 2017 Sep 06;3(9):e00388. doi: 10.1016/j.heliyon.2017.e00388. eCollection 2017 Sep.

Dynamics of sodium current mediated early afterdepolarizations.

Heliyon

Daisuke Sato, Colleen E Clancy, Donald M Bers

Affiliations

  1. Department of Pharmacology, University of California, Davis, CA, United States.

PMID: 28924617 PMCID: PMC5591396 DOI: 10.1016/j.heliyon.2017.e00388

Abstract

Early afterdepolarizations (EADs) have been attributed to two primary mechanisms: 1) recovery from inactivation of the L-type calcium (Ca) channel and/or 2) spontaneous Ca release, which depolarizes the membrane potential through the electrogenic sodium-calcium exchanger (NCX). The sodium (Na) current (

Keywords: Applied mathematics; Biophysics; Cardiology; Cell biology; Medicine; Physiology; Systems biology

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