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Hayashida O, Nakano Y, Hasumi K, et al. Inhibition of Glucan Synthesis by Flavipin-crosslinked Casein Polymers. Biosci Biotechnol Biochem. 1997;61(5):903-904doi: 10.1271/bbb.61.903.
Hayashida, O., Nakano, Y., Hasumi, K., & Endo, A. (1997). Inhibition of Glucan Synthesis by Flavipin-crosslinked Casein Polymers. Bioscience, biotechnology, and biochemistry, 61(5), 903-904. https://doi.org/10.1271/bbb.61.903
Hayashida, Osamu, et al. "Inhibition of Glucan Synthesis by Flavipin-crosslinked Casein Polymers." Bioscience, biotechnology, and biochemistry vol. 61,5 (1997): 903-904. doi: https://doi.org/10.1271/bbb.61.903
Hayashida O, Nakano Y, Hasumi K, Endo A. Inhibition of Glucan Synthesis by Flavipin-crosslinked Casein Polymers. Biosci Biotechnol Biochem. 1997 Jan;61(5):903-904. doi: 10.1271/bbb.61.903. PMID: 28862563.
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Biosci Biotechnol Biochem. 1997 Jan;61(5):903-904. doi: 10.1271/bbb.61.903.

Inhibition of Glucan Synthesis by Flavipin-crosslinked Casein Polymers.

Bioscience, biotechnology, and biochemistry

Osamu Hayashida, Yamaji Nakano, Keiji Hasumi, Akira Endo

Affiliations

  1. a Department of Applied Biological Science, Faculty of Agriculture , Tokyo Noko University , Fuchu-shi, Tokyo 183 , Japan.

PMID: 28862563 DOI: 10.1271/bbb.61.903

Abstract

Mutastein, a casein polymer that inhibits insoluble glucan synthesis by Streptococcus sobrinus, was produced when Aspergillus terreus was grown in a medium containing α-casein. In these experiments, it was shown that flavipin (3,4,5-trihydroxy-6-methyl-o-phthalaldehyde) isolated from cultures of A. terreus caused polymerization of α-casein. Like mutastein, the polymerization products were active in inhibiting insoluble glucan synthesis by S. sobrinus.

Keywords: casein; flavipin; glucan synthesis; mutastein

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