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Smith AJ, Young A, Rohrbach S, et al. Electron-Transfer and Hydride-Transfer Pathways in the Stoltz-Grubbs Reducing System (KOtBu/Et. Angew Chem Int Ed Engl. 2017;56(44):13747-13751doi: 10.1002/anie.201707914.
Smith, A. J., Young, A., Rohrbach, S., O'Connor, E. F., Allison, M., Wang, H. S., Poole, D. L., Tuttle, T., & Murphy, J. A. (2017). Electron-Transfer and Hydride-Transfer Pathways in the Stoltz-Grubbs Reducing System (KOtBu/Et. Angewandte Chemie (International ed. in English), 56(44), 13747-13751. https://doi.org/10.1002/anie.201707914
Smith, Andrew J, et al. "Electron-Transfer and Hydride-Transfer Pathways in the Stoltz-Grubbs Reducing System (KOtBu/Et." Angewandte Chemie (International ed. in English) vol. 56,44 (2017): 13747-13751. doi: https://doi.org/10.1002/anie.201707914
Smith AJ, Young A, Rohrbach S, O'Connor EF, Allison M, Wang HS, Poole DL, Tuttle T, Murphy JA. Electron-Transfer and Hydride-Transfer Pathways in the Stoltz-Grubbs Reducing System (KOtBu/Et. Angew Chem Int Ed Engl. 2017 Oct 23;56(44):13747-13751. doi: 10.1002/anie.201707914. Epub 2017 Oct 02. PMID: 28892585; PMCID: PMC5656899.
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Angew Chem Int Ed Engl. 2017 Oct 23;56(44):13747-13751. doi: 10.1002/anie.201707914. Epub 2017 Oct 02.

Electron-Transfer and Hydride-Transfer Pathways in the Stoltz-Grubbs Reducing System (KOtBu/Et.

Angewandte Chemie (International ed. in English)

Andrew J Smith, Allan Young, Simon Rohrbach, Erin F O'Connor, Mark Allison, Hong-Shuang Wang, Darren L Poole, Tell Tuttle, John A Murphy

Affiliations

  1. Department of Pure and Applied Chemistry, University of Strathclyde, 295 Cathedral Street, Glasgow, G1 1XL, UK.
  2. Flexible Discovery Unit, GlaxoSmithKline Medicines Research Centre, Gunnels Wood Road, Stevenage, SG1 2NY, UK.

PMID: 28892585 PMCID: PMC5656899 DOI: 10.1002/anie.201707914

Abstract

Recent studies by Stoltz, Grubbs et al. have shown that triethylsilane and potassium tert-butoxide react to form a highly attractive and versatile system that shows (reversible) silylation of arenes and heteroarenes as well as reductive cleavage of C-O bonds in aryl ethers and C-S bonds in aryl thioethers. Their extensive mechanistic studies indicate a complex network of reactions with a number of possible intermediates and mechanisms, but their reactions likely feature silyl radicals undergoing addition reactions and S

© 2017 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA.

Keywords: density-functional calculations; electron transfer; hydrides; reaction mechanisms; silicon

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