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Stem Cells Int. 2017;2017:3548435. doi: 10.1155/2017/3548435. Epub 2017 Aug 16.

Guided Bone Regeneration Using Collagen Scaffolds, Growth Factors, and Periodontal Ligament Stem Cells for Treatment of Peri-Implant Bone Defects .

Stem cells international

Peer W Kämmerer, Malte Scholz, Maria Baudisch, Jan Liese, Katharina Wegner, Bernhard Frerich, Hermann Lang

Affiliations

  1. Department of Oral and Maxillofacial Surgery, Facial Plastic Surgery, University Medical Centre Rostock, Schillingallee 35, 18057 Rostock, Germany.
  2. Department of Operative Dentistry and Periodontology, University Medical Centre Rostock, Strempelstraße 13, 18057 Rostock, Germany.

PMID: 28951742 PMCID: PMC5603746 DOI: 10.1155/2017/3548435

Abstract

INTRODUCTION: The aim of the study was an evaluation of different approaches for guided bone regeneration (GBR) of peri-implant defects in an

MATERIALS AND METHODS: In minipigs (

RESULTS: In all groups, new bone formation was seen. Though, when compared to the blank group, no significant differences were detected for all parameters. BIC and NBH in the group with collagen matrix as well as the group with the collagen matrix + GFC were significantly less when compared to the collagen powder group (all:

CONCLUSION: GBR procedures, in combination with CaP-coated implants, will lead to an enhancement of peri-implant bone growth. There was no additional significant enhancement of osseous regeneration when using GFC or PDLSC.

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