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Integr Med Res. 2017 Sep;6(3):231-239. doi: 10.1016/j.imr.2017.06.005. Epub 2017 Jul 08.

Pharmacognostic outlooks on medical herbs of Sasang typology.

Integrative medicine research

Su Hye Lim, Eun Sang Jeon, Jeongyun Lee, Sang Yun Han, Han Chae

Affiliations

  1. Department of Pharmacognosy, Faculty of Pharmacy, Istanbul University, Istanbul, Turkey.
  2. Division of Longevity and Biofunctional Medicine, School of Korean Medicine, Pusan National University, Busan, Korea.
  3. Department of Complementary and Alternative Medicine, Medipol University, Istanbul, Turkey.
  4. Korea Institute of Oriental Medicine, Daejeon, Korea.

PMID: 28951836 PMCID: PMC5605368 DOI: 10.1016/j.imr.2017.06.005

Abstract

The purpose of this study was to review the pharmacognostic characteristics of Sasang type-specific medical herbs and suggest biological mechanisms that might be related to the personalized treatment of the East. Major compounds and their pharmacological activities of medical herbs for each Sasang types were systematically reviewed. The pharmacognostic characteristics of its main compounds were systematically analyzed with previous studies and three web-based databases. Sasang type-specific medical herbs were selected, and biological effects of their phytochemicals were reviewed from the pathophysiological features of each Sasang types. Phenolics were dominant in Tae-Yang type-specific herbs, iridoids and triterpenes with antipyretic and diuretic effects were in So-Yang type-specific, saponins (triterpene saponins and steroidal saponins) with antitussive effects were in Tae-Eum type-specific, and monoterpene and sesquiterpenes with stomachic effect were in So-Eum type-specific herbs. Pharmacognostic understandings on Sasang type-specific medical herbs with consideration of type-specific pathophysiological features were provided for the first time. This study would contribute to in-depth understandings on the pathophysiology of Sasang typology and integration of East-Asian and Western personalized medicine.

Keywords: Sasang typology; medical herb; personalized medicine; pharmacognosy

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