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Bioengineering (Basel). 2017 Jun 28;4(3). doi: 10.3390/bioengineering4030061.

Insights on Osmotic Tolerance Mechanisms in Escherichia coli Gained from an rpoC Mutation.

Bioengineering (Basel, Switzerland)

Yuqi Guo, James Winkler, Katy C Kao

Affiliations

  1. Department of Chemical Engineering, Texas A&M University, College Station, TX 77843, USA. [email protected].
  2. Department of Chemical and Biological Engineering, University of Colorado-Boulder, Boulder, CO 80303, USA. [email protected].
  3. Department of Chemical Engineering, Texas A&M University, College Station, TX 77843, USA. [email protected].

PMID: 28952540 PMCID: PMC5615307 DOI: 10.3390/bioengineering4030061

Abstract

An 84 bp in-frame duplication (K370_A396dup) within the rpoC subunit of RNA polymerase was found in two independent mutants selected during an adaptive laboratory evolution experiment under osmotic stress in

Keywords: E. coli; acetic acid; amino acid; complex phenotype; membrane integrity; osmotic tolerance; rpoC

Conflict of interest statement

The authors declare no conflict of interest.

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