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Bhatt L, Joshi V. . J Intercult Ethnopharmacol. 2017;6(3):284-289doi: 10.5455/jice.20170701075019.
Bhatt, L., & Joshi, V. (2017). . Journal of intercultural ethnopharmacology, 6(3), 284-289. https://doi.org/10.5455/jice.20170701075019
Bhatt, Laxit, and Joshi, Viraj. "." Journal of intercultural ethnopharmacology vol. 6,3 (2017): 284-289. doi: https://doi.org/10.5455/jice.20170701075019
Bhatt L, Joshi V. . J Intercult Ethnopharmacol. 2017 Jul 12;6(3):284-289. doi: 10.5455/jice.20170701075019. eCollection 2017. PMID: 28894627; PMCID: PMC5580954.
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J Intercult Ethnopharmacol. 2017 Jul 12;6(3):284-289. doi: 10.5455/jice.20170701075019. eCollection 2017.

[No title available]

Journal of intercultural ethnopharmacology

Laxit Bhatt, Viraj Joshi

Affiliations

  1. Department of Pharmacology, Shree Devi College of Pharmacy, Mangalore, Karnataka, India.
  2. Department of Pharmacology & Toxicology, Zydus Research Centre, Ahmedabad, Gujarat, India.
  3. Department of Quality Assurance, Shree Devi College of Pharmacy, Mangalore, Karnataka, India.

PMID: 28894627 PMCID: PMC5580954 DOI: 10.5455/jice.20170701075019

Abstract

AIM: The study was undertaken to evaluate the cardioprotective effect of the alcoholic leaf extract of

MATERIALS AND METHODS: Rats were treated with 100 mg/kg of

RESULTS: The MILE treated group showed decrease in serum biomarker enzyme levels and increase in tissue antioxidants levels. Compared to DOX control group, MILE treated animals showed improvement in lipid profile, electrocardiographic parameters, histological score, and mortality.

CONCLUSION: These findings clearly suggest the protective role of alcoholic leaf extract of

Keywords: Anthracycline cardiotoxicity; cardioprotection; chemotherapy adverse effects; oxidative stress; rats

Conflict of interest statement

Conflict of Interest: None declared.

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