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Pillai AN, Shukla S, Rahaman A. An evolutionarily conserved phosphatidate phosphatase maintains lipid droplet number and endoplasmic reticulum morphology but not nuclear morphology. Biol Open. 2017;6(11):1629-1643doi: 10.1242/bio.028233.
Pillai, A. N., Shukla, S., & Rahaman, A. (2017). An evolutionarily conserved phosphatidate phosphatase maintains lipid droplet number and endoplasmic reticulum morphology but not nuclear morphology. Biology open, 6(11), 1629-1643. https://doi.org/10.1242/bio.028233
Pillai, Anoop Narayana, et al. "An evolutionarily conserved phosphatidate phosphatase maintains lipid droplet number and endoplasmic reticulum morphology but not nuclear morphology." Biology open vol. 6,11 (2017): 1629-1643. doi: https://doi.org/10.1242/bio.028233
Pillai AN, Shukla S, Rahaman A. An evolutionarily conserved phosphatidate phosphatase maintains lipid droplet number and endoplasmic reticulum morphology but not nuclear morphology. Biol Open. 2017 Nov 15;6(11):1629-1643. doi: 10.1242/bio.028233. PMID: 28954739; PMCID: PMC5703613.
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Biol Open. 2017 Nov 15;6(11):1629-1643. doi: 10.1242/bio.028233.

An evolutionarily conserved phosphatidate phosphatase maintains lipid droplet number and endoplasmic reticulum morphology but not nuclear morphology.

Biology open

Anoop Narayana Pillai, Sushmita Shukla, Abdur Rahaman

Affiliations

  1. School of Biological Sciences, National Institute of Science Education and Research (NISER)-Bhubaneswar, HBNI, P.O. Jatni, Khurda 752050, Odisha, India.
  2. School of Biological Sciences, National Institute of Science Education and Research (NISER)-Bhubaneswar, HBNI, P.O. Jatni, Khurda 752050, Odisha, India [email protected].

PMID: 28954739 PMCID: PMC5703613 DOI: 10.1242/bio.028233

Abstract

Phosphatidic acid phosphatases are involved in the biosynthesis of phospholipids and triacylglycerol, and also act as transcriptional regulators. Studies to ascertain their role in lipid metabolism and membrane biogenesis are restricted to Opisthokonta and Archaeplastida. Here, we report the role of phosphatidate phosphatase (

© 2017. Published by The Company of Biologists Ltd.

Keywords: Endoplasmic reticulum; Lipid droplet; Lipin; Nuclear membrane expansion; Phosphatidic acid hydrolase; Tetrahymena thermophila

Conflict of interest statement

Competing interestsThe authors declare no competing or financial interests.

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