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Samburova V, Zielinska B, Khlystov A. Do 16 Polycyclic Aromatic Hydrocarbons Represent PAH Air Toxicity?. Toxics. 2017;5(3)doi: 10.3390/toxics5030017.
Samburova, V., Zielinska, B., & Khlystov, A. (2017). Do 16 Polycyclic Aromatic Hydrocarbons Represent PAH Air Toxicity?. Toxics, 5(3), . https://doi.org/10.3390/toxics5030017
Samburova, Vera, et al. "Do 16 Polycyclic Aromatic Hydrocarbons Represent PAH Air Toxicity?." Toxics vol. 5,3 (2017). doi: https://doi.org/10.3390/toxics5030017
Samburova V, Zielinska B, Khlystov A. Do 16 Polycyclic Aromatic Hydrocarbons Represent PAH Air Toxicity?. Toxics. 2017 Aug 15;5(3). doi: 10.3390/toxics5030017. PMID: 29051449; PMCID: PMC5634701.
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Toxics. 2017 Aug 15;5(3). doi: 10.3390/toxics5030017.

Do 16 Polycyclic Aromatic Hydrocarbons Represent PAH Air Toxicity?.

Toxics

Vera Samburova, Barbara Zielinska, Andrey Khlystov

Affiliations

  1. Desert Research Institute, Division of Atmospheric Sciences, 2215 Raggio Parkway, Reno, NV 89512, USA. [email protected].
  2. Desert Research Institute, Division of Atmospheric Sciences, 2215 Raggio Parkway, Reno, NV 89512, USA. [email protected].
  3. Desert Research Institute, Division of Atmospheric Sciences, 2215 Raggio Parkway, Reno, NV 89512, USA. [email protected].

PMID: 29051449 PMCID: PMC5634701 DOI: 10.3390/toxics5030017

Abstract

Estimation of carcinogenic potency based on analysis of 16 polycyclic aromatic hydrocarbons (PAHs) ranked by U.S. Environmental Protection Agency (EPA) is the most popular approach within scientific and environmental air quality management communities. The majority of PAH monitoring projects have been focused on particle-bound PAHs, ignoring the contribution of gas-phase PAHs to the toxicity of PAH mixtures in air samples. In this study, we analyzed the results of 13 projects in which 88 PAHs in both gas and particle phases were collected from different sources (biomass burning, mining operation, and vehicle emissions), as well as in urban air. The aim was to investigate whether 16 particle-bound U.S. EPA priority PAHs adequately represented health risks of inhalation exposure to atmospheric PAH mixtures. PAH concentrations were converted to benzo(a)pyrene-equivalent (BaPeq) toxicity using the toxic equivalency factor (TEF) approach. TEFs of PAH compounds for which such data is not available were estimated using TEFs of close isomers. Total BaPeq toxicities (∑

Keywords: air samples; gas and particle phase PAHs; polycyclic aromatic hydrocarbons; toxic equivalency factor

Conflict of interest statement

The authors declare no conflicts of interest.

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