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Voloshchuk N, Chen L, Li Q, et al. Peptide oligomers from ultra-short peptides using sortase. Biochem Biophys Rep. 2017;10:1-6doi: 10.1016/j.bbrep.2017.02.005.
Voloshchuk, N., Chen, L., Li, Q., & Liang, J. F. (2017). Peptide oligomers from ultra-short peptides using sortase. Biochemistry and biophysics reports, 101-6. https://doi.org/10.1016/j.bbrep.2017.02.005
Voloshchuk, Natalya, et al. "Peptide oligomers from ultra-short peptides using sortase." Biochemistry and biophysics reports vol. 10 (2017): 1-6. doi: https://doi.org/10.1016/j.bbrep.2017.02.005
Voloshchuk N, Chen L, Li Q, Liang JF. Peptide oligomers from ultra-short peptides using sortase. Biochem Biophys Rep. 2017 Feb 20;10:1-6. doi: 10.1016/j.bbrep.2017.02.005. eCollection 2017 Jul. PMID: 28955731; PMCID: PMC5614665.
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Biochem Biophys Rep. 2017 Feb 20;10:1-6. doi: 10.1016/j.bbrep.2017.02.005. eCollection 2017 Jul.

Peptide oligomers from ultra-short peptides using sortase.

Biochemistry and biophysics reports

Natalya Voloshchuk, Long Chen, Qiang Li, Jun F Liang

Affiliations

  1. Department of Chemistry, Chemical Biology, and Biomedical Engineering, Charles V. Schaefer School of Engineering and Sciences, Stevens Institute of Technology, Hoboken, NJ 07030, USA.

PMID: 28955731 PMCID: PMC5614665 DOI: 10.1016/j.bbrep.2017.02.005

Abstract

Sortase A catalyzed ligation of ultra-short peptides leads to inter/intra-molecular transpeptidation to form either linear or cyclic oligomers dependent upon the peptide length. Cyclic peptides were the main products for peptides with more than 15aa. However, for ultra-short (<15aa) peptides, cyclic oligomers became predominant in prolonged reactions. Peptides with 1-3 aminoglycines were equally active but peptide oligomers from peptide containing more than one aminoglycine were prone to hydrolysis.

Keywords: Cyclic peptide; Ligation; Peptide oligomer; Sortase; Ultra-short peptide

References

  1. Curr Cardiol Rev. 2010 Feb;6(1):62-70 - PubMed
  2. Chembiochem. 2008 Mar 25;9(5):802-7 - PubMed
  3. Biochemistry. 2003 Sep 30;42(38):11307-15 - PubMed
  4. J Pept Sci. 2009 Aug;15(8):533-9 - PubMed
  5. Nat Chem Biol. 2007 Nov;3(11):707-8 - PubMed
  6. Peptides. 2009 Aug;30(8):1523-8 - PubMed
  7. Biomacromolecules. 2011 Dec 12;12(12):4196-203 - PubMed
  8. Angew Chem Int Ed Engl. 2011 May 23;50(22):5024-32 - PubMed
  9. Biomacromolecules. 2013 Jul 8;14(7):2326-31 - PubMed
  10. Small. 2010 Feb 5;6(3):421-9 - PubMed
  11. Chem Commun (Camb). 2011 Aug 28;47(32):9218-20 - PubMed
  12. J Med Chem. 2009 Apr 9;52(7):2090-7 - PubMed
  13. J Pept Sci. 2010 Sep;16(9):473-9 - PubMed
  14. Biomacromolecules. 2012 Oct 8;13(10):3327-33 - PubMed
  15. Science. 2006 Mar 17;311(5767):1563-4 - PubMed
  16. Chembiochem. 2011 Jan 3;12(1):38-42 - PubMed
  17. Proc Natl Acad Sci U S A. 2001 May 22;98(11):6056-61 - PubMed
  18. Angew Chem Int Ed Engl. 2012 Sep 10;51(37):9377-80 - PubMed
  19. Ther Deliv. 2012 May;3(5):609-21 - PubMed
  20. Angew Chem Int Ed Engl. 2014 Jun 10;53(24):6115-9 - PubMed
  21. Nat Protoc. 2014 Feb;9(2):253-62 - PubMed
  22. Biol Chem. 2011 Oct;392(10):919-26 - PubMed
  23. Adv Mater. 2009 Oct 5;21(37):3764-3770 - PubMed
  24. Angew Chem Int Ed Engl. 2010 Sep 3;49(37):6545-8 - PubMed
  25. J Am Chem Soc. 2010 Feb 10;132(5):1567-71 - PubMed
  26. PLoS One. 2007 Nov 14;2(11):e1164 - PubMed
  27. Trends Biotechnol. 2011 Sep;29(9):464-72 - PubMed
  28. J Am Chem Soc. 2009 Aug 12;131(31):10800-1 - PubMed
  29. Proc Natl Acad Sci U S A. 2014 Sep 16;111(37):13343-8 - PubMed
  30. J Phys Chem B. 2008 Jun 26;112(25):7631-44 - PubMed
  31. Biomacromolecules. 2012 Oct 8;13(10):3377-87 - PubMed

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