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Jalnapurkar S, Zarrini P, Mehta PK, et al. Role of Stress Cardiac Magnetic Resonance Imaging in Women with Suspected Ischemia but No Obstructive Coronary Artery Disease. J Radiol Nurs. 2017;36(3):180-183doi: 10.1016/j.jradnu.2017.04.016.
Jalnapurkar, S., Zarrini, P., Mehta, P. K., Thomson, L. E. J., Agarwal, M., Samuels, B. A., Shufelt, C. L., Eastwood, J. A., Berman, D., Merz, N. B., & Minissian, M. B. (2017). Role of Stress Cardiac Magnetic Resonance Imaging in Women with Suspected Ischemia but No Obstructive Coronary Artery Disease. Journal of radiology nursing, 36(3), 180-183. https://doi.org/10.1016/j.jradnu.2017.04.016
Jalnapurkar, Sawan, et al. "Role of Stress Cardiac Magnetic Resonance Imaging in Women with Suspected Ischemia but No Obstructive Coronary Artery Disease." Journal of radiology nursing vol. 36,3 (2017): 180-183. doi: https://doi.org/10.1016/j.jradnu.2017.04.016
Jalnapurkar S, Zarrini P, Mehta PK, Thomson LEJ, Agarwal M, Samuels BA, Shufelt CL, Eastwood JA, Berman D, Merz NB, Minissian MB. Role of Stress Cardiac Magnetic Resonance Imaging in Women with Suspected Ischemia but No Obstructive Coronary Artery Disease. J Radiol Nurs. 2017 Sep;36(3):180-183. doi: 10.1016/j.jradnu.2017.04.016. Epub 2017 Aug 30. PMID: 29081724; PMCID: PMC5654630.
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J Radiol Nurs. 2017 Sep;36(3):180-183. doi: 10.1016/j.jradnu.2017.04.016. Epub 2017 Aug 30.

Role of Stress Cardiac Magnetic Resonance Imaging in Women with Suspected Ischemia but No Obstructive Coronary Artery Disease.

Journal of radiology nursing

Sawan Jalnapurkar, Parham Zarrini, Puja K Mehta, Louise E J Thomson, Megha Agarwal, Bruce A Samuels, Chrisandra L Shufelt, Jo-Ann Eastwood, Daniel Berman, Noel Bairey Merz, Margo B Minissian

Affiliations

  1. Women's Heart Center, Cedars-Sinai Heart Institute, Los Angeles, CA.
  2. Division of Cardiology Emory University School of Medicine.
  3. S. Mark Taper Foundation Imaging Center, Cedars-Sinai Medical Center, Los Angeles, CA.

PMID: 29081724 PMCID: PMC5654630 DOI: 10.1016/j.jradnu.2017.04.016

Abstract

OBJECTIVE: Signs and symptoms of ischemia but no obstructive coronary artery disease (CAD) is often a diagnostic dilemma in women. The use of stress cardiac magnetic resonance imaging (CMRI) for advanced diagnostic assessment in these patients is a non-ionizing radiation option, but the diagnostic utility in this population is unknown. We examined the diagnostic role of stress CMRI in our patient population of these women.

METHODS: We analyzed 113 consecutive female patients from 2/2006-11/2007 who had prior cardiac evaluations for signs and symptoms of ischemia but no obstructive CAD who underwent stress CMRI, which included anatomic, functional, adenosine stress perfusion and delayed enhancement imaging.

RESULTS: The population demographics of 113 women included a mean age of 55±12.2 years with an average body mass index (BMI) of 25 ± 4.5. Overall, 43% had hypertension, 4% had diabetes and 3% were smokers. Overall, 80/113 (70%) demonstrated abnormal stress CMRI results. The majority of patients demonstrated findings consistent with subendocardial perfusion abnormalities suggestive of coronary microvascular dysfunction (CMD). Of note, 3 patients (4%) were diagnosed with congenital coronary anomalies or cardiomyopathy not detected in prior cardiac evaluations.

CONCLUSION: Among women with signs and symptoms of ischemia but no obstructive CAD, stress CMRI is frequently abnormal and is valuable in diagnosis of CMD. Stress CMRI appears useful for advanced diagnostic assessment in these diagnostically challenged patients.

Keywords: Myocardial ischemia; cardiac magnetic resonance imaging; coronary microvascular dysfunction

References

  1. J Am Coll Cardiol. 2009 Oct 20;54(17):1561-75 - PubMed
  2. J Am Coll Cardiol. 2006 Feb 7;47(3 Suppl):S4-S20 - PubMed
  3. J Nucl Cardiol. 2002 Mar-Apr;9(2):240-5 - PubMed
  4. Circulation. 2004 Jun 1;109 (21):2518-23 - PubMed
  5. Circulation. 2014 Jul 22;130(4):350-79 - PubMed
  6. JACC Cardiovasc Imaging. 2011 Aug;4(8):862-70 - PubMed
  7. Circulation. 2007 Apr 3;115(13):1769-76 - PubMed
  8. JACC Cardiovasc Imaging. 2011 Aug;4(8):850-61 - PubMed
  9. J Cardiovasc Magn Reson. 2007;9(5):733-40 - PubMed
  10. Curr Atheroscler Rep. 2016 May;18(5):23 - PubMed

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