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Skakkebaek NE, Berthelsen JG. Carcinoma-in-situ of the testis and invasive growth of different types of germ cell tumours. A revised germ cell theory. Int J Androl. 1981;4:26-33doi: 10.1111/j.1365-2605.1981.tb00647.x.
Skakkebaek, N. E., & Berthelsen, J. G. (1981). Carcinoma-in-situ of the testis and invasive growth of different types of germ cell tumours. A revised germ cell theory. International journal of andrology, 426-33. https://doi.org/10.1111/j.1365-2605.1981.tb00647.x
Skakkebaek, Niels E, and Berthelsen, Jørgen G. "Carcinoma-in-situ of the testis and invasive growth of different types of germ cell tumours. A revised germ cell theory." International journal of andrology vol. 4 (1981): 26-33. doi: https://doi.org/10.1111/j.1365-2605.1981.tb00647.x
Skakkebaek NE, Berthelsen JG. Carcinoma-in-situ of the testis and invasive growth of different types of germ cell tumours. A revised germ cell theory. Int J Androl. 1981 Mar;4:26-33. doi: 10.1111/j.1365-2605.1981.tb00647.x. PMID: 29112252.
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Int J Androl. 1981 Mar;4:26-33. doi: 10.1111/j.1365-2605.1981.tb00647.x.

Carcinoma-in-situ of the testis and invasive growth of different types of germ cell tumours. A revised germ cell theory.

International journal of andrology

Niels E Skakkebaek, Jørgen G Berthelsen

Affiliations

  1. Laboratory of Reproductive Biology, University Department of Obstetrics and Gynaecology YA, Rigshospitalet, CopenhagenUniversity Department of Paediatrics G, Rigshospitalet, CopenhagenUniversity Department of Gynaecology and Obstetrics, Herlev Hospital, Copenhagen.

PMID: 29112252 DOI: 10.1111/j.1365-2605.1981.tb00647.x

Abstract

The hypothesis is proposed that seminomas and non-seminomas are histogenetically closely related and both types of germ cell tumours may originate from a common precursor cell: namely the germ cell showing the carcinoma-in-situ pattern. However, it is suggested that the spermatocytic seminoma is an exception as it may originate from spermatocytes.

Keywords: carcinoma-in-situ; germ cell; testicular neoplasia; testis

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