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Jeka S, Dura M, Żuchowski P, et al. The role of ultrasonography in monitoring long-standing rheumatoid arthritis: a pilot study. Reumatologia. 2017;55(4):177-182doi: 10.5114/reum.2017.69781.
Jeka, S., Dura, M., Żuchowski, P., Zwierko, B., Wojciechowski, R., & Cresswell, K. (2017). The role of ultrasonography in monitoring long-standing rheumatoid arthritis: a pilot study. Reumatologia, 55(4), 177-182. https://doi.org/10.5114/reum.2017.69781
Jeka, Sławomir, et al. "The role of ultrasonography in monitoring long-standing rheumatoid arthritis: a pilot study." Reumatologia vol. 55,4 (2017): 177-182. doi: https://doi.org/10.5114/reum.2017.69781
Jeka S, Dura M, Żuchowski P, Zwierko B, Wojciechowski R, Cresswell K. The role of ultrasonography in monitoring long-standing rheumatoid arthritis: a pilot study. Reumatologia. 2017;55(4):177-182. doi: 10.5114/reum.2017.69781. Epub 2017 Aug 31. PMID: 29056772; PMCID: PMC5647536.
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Reumatologia. 2017;55(4):177-182. doi: 10.5114/reum.2017.69781. Epub 2017 Aug 31.

The role of ultrasonography in monitoring long-standing rheumatoid arthritis: a pilot study.

Reumatologia

Sławomir Jeka, Marta Dura, Paweł Żuchowski, Beata Zwierko, Rafał Wojciechowski, Cresswell

Affiliations

  1. Jan Biziel University Hospital No. 2, Department of Rheumatology and Connective Tissue Diseases, Bydgoszcz, Collegium Medicum in Bydgoszcz, UMK, Torun, Poland.
  2. Jan Biziel University Hospital No. 2, Department of Radiology, Bydgoszcz, Poland.

PMID: 29056772 PMCID: PMC5647536 DOI: 10.5114/reum.2017.69781

Abstract

OBJECTIVE: Rheumatoid arthritis (RA) is a condition that poses many diagnostic problems. As a result, it is often diagnosed too late, which makes effective treatment more difficult. The course of the disease is chronic, and it causes irreversible changes in the musculoskeletal system, as well as bone destruction, and this in turn impairs the proper monitoring of the treatment. Therefore, in order to assess the treatment's efficacy, as well as a clinical examination of the patient and laboratory tests, diagnostic imaging is being used more frequently in routine practice. The aim of this paper is to assess the usefulness of power Doppler ultrasonography in the assessment of MCP joints in patients with chronic RA (LSRA), in comparison with DAS28, X-ray, and MRI.

MATERIAL AND METHODS: The study involved 26 patients with LSRA, treated with biologics. It lasted for a year. At the moment of enrolment, the condition had lasted for a minimum of 5 years, and DAS28 was > 5.1. The patients had visits every three months. During every visit, a PDUS test was performed and the DAS28 was determined. In the first and last month of the study the patients underwent X-ray and MRI tests.

RESULTS: At the end of the study, the DAS28 of 26 (100%) patients was lower or equal to 3.2. Based on PDUS and MRI tests, no synovitis was found in 21 (81%) and 18 (69%) patients, respectively. According to the MRI results, radiological changes progressed in 5 (19%) of them. All patients who showed progress of radiological changes also had visible synovitis during their PDUS test.

CONCLUSIONS: PDUS in patients with LSRA can be helpful in selecting patients, who are likely to develop a progression of radiological changes.

Keywords: ; MRI; rheumatoid arthritis; ultrasonography

Conflict of interest statement

The authors declare no conflict of interest.

References

  1. J Rheumatol. 2011 Sep;38(9):2063-7 - PubMed
  2. Ann Rheum Dis. 2011 Jan;70(1):172-5 - PubMed
  3. Curr Opin Rheumatol. 2016 May;28(3):323-9 - PubMed
  4. Arthritis Rheum. 2000 Dec;43(12 ):2762-70 - PubMed
  5. Semin Arthritis Rheum. 2012 Jun;41(6):761-7 - PubMed
  6. BioDrugs. 2016 Apr;30(2):105-15 - PubMed
  7. Ann Rheum Dis. 2015 May;74(5):806-12 - PubMed
  8. Ann Rheum Dis. 2016 Jun;75(6):1043-50 - PubMed
  9. Ann Rheum Dis. 2005 Jun;64(6):899-905 - PubMed
  10. Mod Rheumatol. 2014 Jan;24(1):60-8 - PubMed
  11. Clin Exp Rheumatol. 2012 Sep-Oct;30(5):649-51 - PubMed
  12. Ann Rheum Dis. 2017 Jun;76(6):960-977 - PubMed
  13. RMD Open. 2017 Mar 30;3(1):e000394 - PubMed
  14. Arthritis Rheum. 2011 Jul;63(7):1804-11 - PubMed
  15. J Rheumatol. 2001 Apr;28(4):881-6 - PubMed
  16. Clin Exp Rheumatol. 2005 Sep-Oct;23(5 Suppl 39):S100-8 - PubMed
  17. Reumatologia. 2016;54(4):170-176 - PubMed
  18. Clin Rheumatol. 2017 Feb;36(2):261-267 - PubMed
  19. Arthritis Res Ther. 2006;8(2):R52 - PubMed

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