J Geriatr Cardiol. 2017 Sep;14(9):575-581. doi: 10.11909/j.issn.1671-5411.2017.09.007.
Clinical outcomes of radiofrequency catheter ablation of atrial fibrillation in octogenarians-10-year experience of a one high-volume center.
Journal of geriatric cardiology : JGC
Alan Bulava, Jiri Hanis, Ladislav Dusek
Affiliations
Affiliations
- Department of Cardiology, Ceske Budejovice Hospital, Ceske Budejovice, Czech Republic.
- Faculty of Medicine and Dentistry, Palacky University, Olomouc, Czech Republic.
- Faculty of Health and Social Sciences, University of South Bohemia in Ceske Budejovice, Czech Republic.
- Institute of Biostatistics and Analyses, Faculty of Medicine, Masaryk University, Brno, Czech Republic.
PMID: 29056956
PMCID: PMC5641645 DOI: 10.11909/j.issn.1671-5411.2017.09.007
Abstract
BACKGROUND: Prevalence of atrial fibrillation (AF) increases with age. Radiofrequency catheter ablation (RFCA) is an established treatment option superior to antiarrhythmics (AAs). In this study, we investigated safety and efficacy of RFCA of AF in octogenarians.
METHODS: From our database, we extracted procedural and follow-up data for patients ≥ 80 years with symptomatic AF undergoing RFCA and compared this population to RFCA patients ≤ 50 years. All patients underwent pulmonary vein isolation (PVI) supplemented by linear lesions in PVI-nonresponders. Arrhythmia-free survival was assessed using seven day Holter every three months post procedure. All patients completed their 12 months follow-up.
RESULTS: Fifty patients aged ≥ 80 years (80.5 ± 1.6 years) were compared to 259 patients aged ≤ 50 years (43.5 ± 5.5 years). The RFCA complication rate did not vary between groups. No differences in procedural characteristics were seen after being analyzed by type of AF. Among patients with paroxysmal AF, 71.4% octogenarian
CONCLUSIONS: RFCA is a safe and effective strategy to achieve normal sinus rhythm in a highly selected group of octogenarians. Paroxysmal AF ablation in octogenarians has similar clinical effectiveness as that seen in much younger patients. Non-paroxysmal AF ablation has lower, but still reasonable clinical effectiveness.
Keywords: Atrial fibrillation; Catheter ablation; Effectiveness; Octogenarians; Safety; The elderly
References
- Stroke. 1991 Mar;22(3):312-8 - PubMed
- Pacing Clin Electrophysiol. 2010 Feb;33(2):146-52 - PubMed
- Europace. 2013 Jan;15(1):24-32 - PubMed
- Heart Fail Rev. 2012 Sep;17(4-5):597-613 - PubMed
- J Cardiovasc Electrophysiol. 2012 Jul;23(7):687-93 - PubMed
- JAMA. 2010 Jan 27;303(4):333-40 - PubMed
- JAMA. 2005 Jun 1;293(21):2634-40 - PubMed
- Ann Intern Med. 2013 Mar 5;158(5 Pt 1):338-46 - PubMed
- Circ Arrhythm Electrophysiol. 2010 Feb;3(1):32-8 - PubMed
- Stroke. 1996 Oct;27(10):1760-4 - PubMed
- JAMA Cardiol. 2017 Jul 1;2(7):812-813 - PubMed
- Europace. 2016 Apr;18(4):543-9 - PubMed
- Europace. 2007 Aug;9(8):613-20 - PubMed
- Eur Heart J. 2006 Apr;27(8):949-53 - PubMed
- J Cardiovasc Electrophysiol. 2004 Jan;15(1):8-13 - PubMed
- J Am Coll Cardiol. 2004 Jul 7;44(1):109-16 - PubMed
- Am J Cardiol. 1996 Dec 15;78(12):1433-6 - PubMed
- J Cardiovasc Electrophysiol. 2008 Aug;19(8):807-11 - PubMed
- Circulation. 2008 Dec 9;118(24):2498-505 - PubMed
- Curr Opin Cardiol. 2011 Jan;26(1):25-9 - PubMed
- J Cardiovasc Electrophysiol. 2008 Jun;19(6):621-6 - PubMed
- Eur Heart J. 2016 Oct 7;37(38):2893-2962 - PubMed
- J Cardiovasc Electrophysiol. 2005 May;16(5):457-61 - PubMed
- Int J Cardiol. 2010 Nov 5;145(1):147-8 - PubMed
- J Cardiovasc Electrophysiol. 2008 Jun;19(6):627-31 - PubMed
- Heart Rhythm. 2010;7(2):167-72 - PubMed
- Stroke. 2001 Nov;32(11):2559-66 - PubMed
- JAMA. 2001 May 9;285(18):2370-5 - PubMed
Publication Types