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A A Pract. 2018 Mar 01;10(5):97-99. doi: 10.1213/XAA.0000000000000639.

Malignant Hyperthermia Versus Thyroid Storm in a Patient With Symptomatic Graves Disease: A Case Report.

A&A practice

Sara M Strowd, Michael B Majewski, Jennifer Asteris

Affiliations

  1. From the Department of Anesthesiology, Loyola University Medical Center, Maywood, Illinois.

PMID: 29028638 DOI: 10.1213/XAA.0000000000000639

Abstract

Malignant hyperthermia and thyroid storm are intraoperative emergencies with overlapping symptoms but different treatment protocols. We faced this diagnostic dilemma in a 25-year-old patient with symptomatic hyperthyroidism, elevated free T3 and free T4, and low thyroid-stimulating hormone from Graves disease despite treatment with propranolol 80 mg daily and methimazole 40 mg every 8 hours. During thyroidectomy, he developed hyperthermia and hypercarbia without tachycardia. When the rate of rise of PaCO2 and temperature accelerated, we treated the patient for malignant hyperthermia, a diagnosis subsequently confirmed by genetic testing.

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