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Mol Clin Oncol. 2017 Nov;7(5):815-819. doi: 10.3892/mco.2017.1402. Epub 2017 Sep 01.

Hepatic epithelioid hemangioendothelioma with metastasis to the mesentery of the small intestine: A case report.

Molecular and clinical oncology

Daichi Nakamura, Yasushi Adachi, Yasuaki Nakashima, Noriko Sakaida, Hiroyuki Narahara, Ming Shi, Michihiko Tsubono, Susumu Ikehara

Affiliations

  1. Department of Surgery, Toyooka Hospital, Toyooka, Hyogo 668-8501, Japan.
  2. Department of Diagnostic Pathology, Toyooka Hospital, Toyooka, Hyogo 668-8501, Japan.
  3. Department of Pathology and Cytology Center, BML Group PCL Japan, Ibaraki, Osaka 567-0865, Japan.
  4. Department of Pathology, Osaka City University Graduate School of Medicine, Osaka 545-8586, Japan.
  5. Department of Diagnostic Pathology, Kakogawa Central Hospital, Kakogawa, Hyogo 675-8611, Japan.
  6. Department of Medical Oncology, Nishinomiya Hospital, Nishinomiya, Hyogo 662-0918, Japan.
  7. School of Public Health, Guangdong Medical University, Dongguan, Guangdong 523808, P.R. China.
  8. Emeritus Professor, Kansai Medical University, Hirakata, Osaka 573-1010, Japan.

PMID: 29142751 PMCID: PMC5666655 DOI: 10.3892/mco.2017.1402

Abstract

Epithelioid hemangioendothelioma (EHAE) is a vascular tumor which, due to its rarity, is often misdiagnosed as other hepatic tumors based on radiological characteristics. We herein report a case of EHAE in the liver and the mesentery of the small intestine. A 64-year-old asymptomatic woman was admitted to the hospital due to a hepatic tumor identified using computed tomography (CT). An enhanced CT scan revealed multiple tumors in the liver and a tumor in the mesentery. One of the hepatic tumors and the mesenteric tumor were resected and histologically examined. The two tumors exhibited similar histological characteristics and were diagnosed as EHAE. When multiple tumors are found in the liver, EHAE should be included in the differential diagnosis, as the prognosis of EHAE differs from that of carcinoma or benign tumors.

Keywords: epithelioid hemangioendothelioma; female patient; hormonal therapy; liver; mesentery

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