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Amjad W, Qureshi W, Farooq A, et al. Gastrointestinal Side Effects of Antiarrhythmic Medications: A Review of Current Literature. Cureus. 2017;9(9):e1646doi: 10.7759/cureus.1646.
Amjad, W., Qureshi, W., Farooq, A., Sohail, U., Khatoon, S., Pervaiz, S., Narra, P., Hasan, S. M., Ali, F., Ullah, A., & Guttmann, S. (2017). Gastrointestinal Side Effects of Antiarrhythmic Medications: A Review of Current Literature. Cureus, 9(9), e1646. https://doi.org/10.7759/cureus.1646
Amjad, Waseem, et al. "Gastrointestinal Side Effects of Antiarrhythmic Medications: A Review of Current Literature." Cureus vol. 9,9 (2017): e1646. doi: https://doi.org/10.7759/cureus.1646
Amjad W, Qureshi W, Farooq A, Sohail U, Khatoon S, Pervaiz S, Narra P, Hasan SM, Ali F, Ullah A, Guttmann S. Gastrointestinal Side Effects of Antiarrhythmic Medications: A Review of Current Literature. Cureus. 2017 Sep 03;9(9):e1646. doi: 10.7759/cureus.1646. PMID: 29142794; PMCID: PMC5669531.
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Cureus. 2017 Sep 03;9(9):e1646. doi: 10.7759/cureus.1646.

Gastrointestinal Side Effects of Antiarrhythmic Medications: A Review of Current Literature.

Cureus

Waseem Amjad, Waqas Qureshi, Ali Farooq, Umair Sohail, Salma Khatoon, Sarah Pervaiz, Pratyusha Narra, Syeda M Hasan, Farman Ali, Aman Ullah, Steven Guttmann

Affiliations

  1. Forest Hills Hospital, Northshore-Long Island Jewish Health System.
  2. Internal Medicine, Wake Forest Baptist Hospital.
  3. Internal Medicine, West Virginia University - Charleston Division.
  4. Gastroenterology and Hepatology, East Texas Medical Center.
  5. Internal Medicine, Northwell - Long Island Jewish Forest Hills Hospital.
  6. Medicine, Northwell - Long Island Jewish Forest Hills Hospital.
  7. Medicine, St.john Hospital and Medical Center, Detroit.
  8. Internal Medicine, St Joseph Mercy Oakland Hospital.
  9. Digestive Diseases, Northwell - Long Island Jewish Forest Hills Hospital.

PMID: 29142794 PMCID: PMC5669531 DOI: 10.7759/cureus.1646

Abstract

Antiarrhythmic drugs are commonly prescribed cardiac drugs. Due to their receptor mimicry with several of the gastrointestinal tract receptors, they can frequently lead to gastrointestinal side effects. These side effects are the most common reasons for discontinuation of these drugs by the patients. Knowledge of these side effects is important for clinicians that manage antiarrhythmic drugs. This review focuses on the gastrointestinal side effects of these drugs and provides a detailed up-to-date literature review of the side effects of these drugs. The review provides case reports reported in the literature as well as possible mechanisms that lead to gastrointestinal side effects.

Keywords: antiarrhythmic drugs; cardiac drugs; cardiac pharmacology; drug side effects; gastrointestinal side effects

Conflict of interest statement

The authors have declared that no competing interests exist.

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