Display options
Cite
Pak S, Kilgore A, Thornhill R, et al. Unprovoked Pulmonary Embolism in a Young Patient with Marfan Syndrome. Cureus. 2017;9(9):e1655doi: 10.7759/cureus.1655.
Pak, S., Kilgore, A., Thornhill, R., Rako, K., Meier, A., Pora, G., Costello, J. M., & Dee, C. (2017). Unprovoked Pulmonary Embolism in a Young Patient with Marfan Syndrome. Cureus, 9(9), e1655. https://doi.org/10.7759/cureus.1655
Pak, Stella, et al. "Unprovoked Pulmonary Embolism in a Young Patient with Marfan Syndrome." Cureus vol. 9,9 (2017): e1655. doi: https://doi.org/10.7759/cureus.1655
Pak S, Kilgore A, Thornhill R, Rako K, Meier A, Pora G, Costello JM, Dee C. Unprovoked Pulmonary Embolism in a Young Patient with Marfan Syndrome. Cureus. 2017 Sep 05;9(9):e1655. doi: 10.7759/cureus.1655. PMID: 29142803; PMCID: PMC5669530.
Copy Download .nbib Format: NLM
Share it on

Cureus. 2017 Sep 05;9(9):e1655. doi: 10.7759/cureus.1655.

Unprovoked Pulmonary Embolism in a Young Patient with Marfan Syndrome.

Cureus

Stella Pak, Andrew Kilgore, Rosanne Thornhill, Kyle Rako, Ali Meier, Gavriella Pora, Jillian M Costello, Christine Dee

Affiliations

  1. Internal Medicine, Kettering Medical Center.
  2. Wright State University Boonshoft School of Medicine.
  3. Loma Linda University School of Medicine.
  4. Liberty University College of Osteopathic Medicine.

PMID: 29142803 PMCID: PMC5669530 DOI: 10.7759/cureus.1655

Abstract

Marfan syndrome is a rare connective tissue disorder with a prevalence of approximately 2 to 3 per 10,000 individuals. There have been some reports of young patients with Marfan syndrome developing arteriovenous thromboembolism. These events were unprovoked and recurrent. Owing to its rarity, hypercoagulopathy and other metabolic derangement in patients with Marfan syndrome remains largely unknown. Herein, we report a case of a young man with Marfan syndrome who had myocardial infarction and pulmonary embolism. We hope that this case adds to the scant body of knowledge about this patient population.

Keywords: chest pain; marfan syndrome; pulmonary embolism

Conflict of interest statement

The authors have declared that no competing interests exist.

References

  1. Br J Pharmacol. 2007 Apr;150(8):1075-83 - PubMed
  2. Circulation. 1999 Feb 23;99(7):909-15 - PubMed
  3. Lancet. 2005 Dec 3;366(9501):1965-76 - PubMed
  4. Int J Cardiol. 2013 Sep 10;167(6):2539-45 - PubMed
  5. J Intern Med. 1997 Mar;241(3):221-6 - PubMed
  6. Pediatr Cardiol. 2006 Nov-Dec;27(6):755-8 - PubMed
  7. J Am Coll Cardiol. 2003 Jan 15;41(2):329-32 - PubMed
  8. Arterioscler Thromb Vasc Biol. 2004 Mar;24(3):399-404 - PubMed

Publication Types