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Indian J Clin Biochem. 2017 Oct;32(4):487-492. doi: 10.1007/s12291-016-0625-2. Epub 2016 Nov 17.

Erythrocyte Membrane Bound ATPase and Antioxidant Enzyme Changes Associated with Vascular Calcification is Reduced by Sodium Thiosulfate.

Indian journal of clinical biochemistry : IJCB

Ramya Ramani, Abirami Ramachandran, Sriram Ravindran, Gino A Kurian

Affiliations

  1. School of Chemical and Biotechnology, SASTRA University, Thanjavur, India.
  2. Vascular Biology Lab, SASTRA University, Thanjavur, 613401 India.

PMID: 29062183 PMCID: PMC5634975 DOI: 10.1007/s12291-016-0625-2

Abstract

Sodium thiosulfate (STS), a cyanide antidote has been reported to possess antioxidant and calcium chelation effects, useful for the treatment of renal failure due to vascular calcification and urolithiasis. The present study investigated the in vivo modulatory effects of STS on erythrocyte calcium, phosphorous levels, lipid peroxidation, antioxidant enzyme and membrane ATPase activities (Ca

Keywords: ATPase activity; Adenine; Erythrocytes; Oxidative stress; Vascular calcification

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