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He W, Liu M, Huang P, et al. Discovery of tanshinone derivatives with anti-MRSA activity via targeted bio-transformation. Synth Syst Biotechnol. 2016;1(3):187-194doi: 10.1016/j.synbio.2016.05.002.
He, W., Liu, M., Huang, P., Abdel-Mageed, W. M., Han, J., Watrous, J. D., Nguyen, D. D., Wang, W., Song, F., Dai, H., Zhang, J., Quinn, R. J., Grkovi, T., Luo, H., Zhang, L., & Liu, X. (2016). Discovery of tanshinone derivatives with anti-MRSA activity via targeted bio-transformation. Synthetic and systems biotechnology, 1(3), 187-194. https://doi.org/10.1016/j.synbio.2016.05.002
He, Wenni, et al. "Discovery of tanshinone derivatives with anti-MRSA activity via targeted bio-transformation." Synthetic and systems biotechnology vol. 1,3 (2016): 187-194. doi: https://doi.org/10.1016/j.synbio.2016.05.002
He W, Liu M, Huang P, Abdel-Mageed WM, Han J, Watrous JD, Nguyen DD, Wang W, Song F, Dai H, Zhang J, Quinn RJ, Grkovi T, Luo H, Zhang L, Liu X. Discovery of tanshinone derivatives with anti-MRSA activity via targeted bio-transformation. Synth Syst Biotechnol. 2016 Jul 01;1(3):187-194. doi: 10.1016/j.synbio.2016.05.002. eCollection 2016 Sep. PMID: 29062942; PMCID: PMC5640788.
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Synth Syst Biotechnol. 2016 Jul 01;1(3):187-194. doi: 10.1016/j.synbio.2016.05.002. eCollection 2016 Sep.

Discovery of tanshinone derivatives with anti-MRSA activity via targeted bio-transformation.

Synthetic and systems biotechnology

Wenni He, Miaomiao Liu, Pei Huang, Wael M Abdel-Mageed, Jianying Han, Jeramie D Watrous, Don D Nguyen, Wenzhao Wang, Fuhang Song, Huanqin Dai, Jingyu Zhang, Ronald J Quinn, Tanja Grkovi, Houwei Luo, Lixin Zhang, Xueting Liu

Affiliations

  1. Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.
  2. Graduate University of Chinese Academy of Sciences, Beijing 100049, China.
  3. Eskitis Institute, Griffith University, Brisbane, QLD 4111, Australia.
  4. Department of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
  5. Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt.
  6. Department of Chemistry & Biochemistry, University of California San Diego, La Jolla, CA 92093, United States.
  7. State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.
  8. Department of Natural Products, China Pharmaceutical University, Nanjing 210009, China.

PMID: 29062942 PMCID: PMC5640788 DOI: 10.1016/j.synbio.2016.05.002

Abstract

Two potent anti-MRSA tanshinone glycosides (

Keywords: Biotransformation; Glycosylation; Mucor rouxianus; Tanshinone IIA

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