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Hearn KN, Nalder TD, Cox RP, et al. Modular synthesis of 4-aminocarbonyl substituted 1,8-naphthalimides and application in single molecule fluorescence detection. Chem Commun (Camb). 2017;53(91):12298-12301doi: 10.1039/c7cc07922b.
Hearn, K. N., Nalder, T. D., Cox, R. P., Maynard, H. D., Bell, T. D. M., Pfeffer, F. M., & Ashton, T. D. (2017). Modular synthesis of 4-aminocarbonyl substituted 1,8-naphthalimides and application in single molecule fluorescence detection. Chemical communications (Cambridge, England), 53(91), 12298-12301. https://doi.org/10.1039/c7cc07922b
Hearn, K N, et al. "Modular synthesis of 4-aminocarbonyl substituted 1,8-naphthalimides and application in single molecule fluorescence detection." Chemical communications (Cambridge, England) vol. 53,91 (2017): 12298-12301. doi: https://doi.org/10.1039/c7cc07922b
Hearn KN, Nalder TD, Cox RP, Maynard HD, Bell TDM, Pfeffer FM, Ashton TD. Modular synthesis of 4-aminocarbonyl substituted 1,8-naphthalimides and application in single molecule fluorescence detection. Chem Commun (Camb). 2017 Nov 14;53(91):12298-12301. doi: 10.1039/c7cc07922b. PMID: 29094133.
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Chem Commun (Camb). 2017 Nov 14;53(91):12298-12301. doi: 10.1039/c7cc07922b.

Modular synthesis of 4-aminocarbonyl substituted 1,8-naphthalimides and application in single molecule fluorescence detection.

Chemical communications (Cambridge, England)

K N Hearn, T D Nalder, R P Cox, H D Maynard, T D M Bell, F M Pfeffer, T D Ashton

Affiliations

  1. Centre for Chemistry and Biotechnology, School of Life and Environmental Sciences, Deakin University, Waurn Ponds, 3216, Australia. [email protected].

PMID: 29094133 DOI: 10.1039/c7cc07922b

Abstract

Robust methodology to install amide, carbamate, urea and sulfonamide functionality to the 1,8-naphthalimide scaffold has been developed and exemplified. New benzamidonaphthalimide 6, synthesised using this approach, was found to be sensitive to base whereupon fluorescence emission strongly increases (>10-fold) and red-shifts (>4000 cm

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