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Vet Med Sci. 2016 Jun 06;2(3):179-190. doi: 10.1002/vms3.32. eCollection 2016 Aug.

A phase I clinical study to evaluate safety of orally administered, genetically engineered .

Veterinary medicine and science

Sara E Fritz, Michael S Henson, Emily Greengard, Amber L Winter, Kathleen M Stuebner, Una Yoon, Vicki L Wilk, Antonella Borgatti, Lance B Augustin, Jaime F Modiano, Daniel A Saltzman

Affiliations

  1. Animal Cancer Care and Research ProgramUniversity of MinnesotaSt. PaulMinnesotaUSA.
  2. Department of Veterinary Clinical SciencesCollege of Veterinary MedicineUniversity of MinnesotaSt. PaulMinnesotaUSA.
  3. Masonic Caner CenterUniversity of MinnesotaMinneapolisMinnesotaUSA.
  4. Department of Pediatric Hematology/OncologySchool of Medicine and Masonic Children's HospitalUniversity of MinnesotaMinneapolisMinnesotaUSA.
  5. Clinical Investigation CenterCollege of Veterinary MedicineUniversity of MinnesotaSt. PaulMinnesotaUSA.
  6. Department of SurgeryDivision of Pediatric SurgerySchool of MedicineUniversity of MinnesotaMinneapolisMinnesotaUSA.
  7. Center for ImmunologyUniversity of MinnesotaMinneapolisMinnesotaUSA.

PMID: 29067193 PMCID: PMC5645873 DOI: 10.1002/vms3.32

Abstract

We conducted a prospective phase I study to evaluate safety of an orally administered

Keywords: Interleukin‐2; Salmonella; canine; immunotherapy; osteosarcoma

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