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Jannoo Z, Wah YB, Lazim AM, et al. Examining diabetes distress, medication adherence, diabetes self-care activities, diabetes-specific quality of life and health-related quality of life among type 2 diabetes mellitus patients. J Clin Transl Endocrinol. 2017;9:48-54doi: 10.1016/j.jcte.2017.07.003.
Jannoo, Z., Wah, Y. B., Lazim, A. M., & Hassali, M. A. (2017). Examining diabetes distress, medication adherence, diabetes self-care activities, diabetes-specific quality of life and health-related quality of life among type 2 diabetes mellitus patients. Journal of clinical & translational endocrinology, 948-54. https://doi.org/10.1016/j.jcte.2017.07.003
Jannoo, Zeinab, et al. "Examining diabetes distress, medication adherence, diabetes self-care activities, diabetes-specific quality of life and health-related quality of life among type 2 diabetes mellitus patients." Journal of clinical & translational endocrinology vol. 9 (2017): 48-54. doi: https://doi.org/10.1016/j.jcte.2017.07.003
Jannoo Z, Wah YB, Lazim AM, Hassali MA. Examining diabetes distress, medication adherence, diabetes self-care activities, diabetes-specific quality of life and health-related quality of life among type 2 diabetes mellitus patients. J Clin Transl Endocrinol. 2017 Jul 26;9:48-54. doi: 10.1016/j.jcte.2017.07.003. eCollection 2017 Sep. PMID: 29067270; PMCID: PMC5651286.
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J Clin Transl Endocrinol. 2017 Jul 26;9:48-54. doi: 10.1016/j.jcte.2017.07.003. eCollection 2017 Sep.

Examining diabetes distress, medication adherence, diabetes self-care activities, diabetes-specific quality of life and health-related quality of life among type 2 diabetes mellitus patients.

Journal of clinical & translational endocrinology

Zeinab Jannoo, Yap Bee Wah, Alias Mohd Lazim, Mohamed Azmi Hassali

Affiliations

  1. University of Mauritius, Faculty of Social Studies and Humanities, Department of Economics and Statistics, Réduit, Mauritius.
  2. Universiti Teknologi MARA, Faculty of Computer and Mathematical Sciences, Centre of Statistical and Decision Science Studies, Sek 1, Shah Alam, Malaysia.
  3. Universiti Sains Malaysia, School of Pharmaceutical Sciences, Penang, Malaysia.

PMID: 29067270 PMCID: PMC5651286 DOI: 10.1016/j.jcte.2017.07.003

Abstract

AIMS: Health-Related Quality of Life (HRQoL) has been increasing attention in health outcome studies. Factors that individually influence HRQoL, diabetes self-care behaviors, and medication adherence have been widely investigated; however, most previous studies have not tested an integrated association between multiple health outcomes. The purpose of this study was to formulate a hypothetical structural equation model linking HRQoL, diabetes distress, diabetes self-care activities, medication adherence and diabetes-dependent QoL in patients with Type 2 Diabetes Mellitus (T2DM).

METHODS: A cross-sectional study design was employed, and 497 patients with T2DM were recruited from outpatient clinics in three public hospitals and one government clinic. The patients completed a series of questionnaires. The hypothetical model was tested using Structural Equation Modeling (SEM) analysis.

RESULTS: The values of the multiple fit indices indicated that the proposed model provided a good fit to the data. SEM results showed that medication adherence (MMAS) had a significant direct effect on diabetes distress (PAID) (Beta = -0.20). The self-care activities (SDSCA) construct was significantly related to PAID (Beta = -0.24). SDSCA was found to have a significant relationship with HRQoL (SF-36) (Beta = 0.11). Additionally, diabetes distress had a significant effect (Beta = -0.11) on HRQoL of patients. Finally, ADDQoL had a significant effect on HRQoL (Beta = 0.12).

CONCLUSIONS: The various health outcome indicators such as self-care behaviors, diabetes distress, medication adherence and diabetes-dependent QoL need to be considered in clinical practice for enhancing HRQoL in those patients.

Keywords: Diabetes distress; Health-related quality of life; Medication adherence; Self-care activities; Structural equation modeling; Type 2 diabetes mellitus

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