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Korean J Pain. 2017 Oct;30(4):250-257. doi: 10.3344/kjp.2017.30.4.250. Epub 2017 Sep 29.

Vitamin D and fibromyalgia: a meta-analysis.

The Korean journal of pain

Atekeh Hadinezhad Makrani, Mahdi Afshari, Marayam Ghajar, Zahra Forooghi, Mahmood Moosazadeh

Affiliations

  1. Gastrointestinal Cancer Research Center, Mazandaran University of Medical Sciences, Sari, Iran.
  2. Department of Community Medicine, Zabol University of Medical Sciences, Zabol, Iran.
  3. Health Science Research Center, Addiction Institute, Mazandaran University of Medical Sciences, Sari, Iran.

PMID: 29123619 PMCID: PMC5665736 DOI: 10.3344/kjp.2017.30.4.250

Abstract

Vitamin D is a cofactor responsible for autoimmune disorders. There is no agreement in the studies investigating the association between vitamin D and fibromyalgia. This study aims to combine the conflicting results of the primary studies which compared these patients with control groups regarding the serum concentration of vitamin D. This meta-analysis has been designed based on PRISMA guidelines. Relevant keywords were searched in PubMed, Science direct, Scopus, Cochrane, and Google scholar and primary studies were selected. After screening the eligible studies according to inclusion/exclusion criteria, we investigated the risk of bias in the selected studies and also the heterogeneity between the primary results using Cochrane (Q) and I-squared (I

Keywords: Eligibility determination; Fibromyalgia; Meta-analysis; Myofascial pain syndrome; Pain; Statistics; Vitamin D

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