Display options
Cite
Sato C, Kamijo Y. An unexpected prolonged coma due to a pharmacobezoar formed from Vegetamine A® tablet ingestion. Acute Med Surg. 2014;2(1):60-63doi: 10.1002/ams2.58.
Sato, C., & Kamijo, Y. (2015). An unexpected prolonged coma due to a pharmacobezoar formed from Vegetamine A® tablet ingestion. Acute medicine & surgery, 2(1), 60-63. https://doi.org/10.1002/ams2.58
Sato, Chie, and Kamijo, Yoshito. "An unexpected prolonged coma due to a pharmacobezoar formed from Vegetamine A® tablet ingestion." Acute medicine & surgery vol. 2,1 (2015): 60-63. doi: https://doi.org/10.1002/ams2.58
Sato C, Kamijo Y. An unexpected prolonged coma due to a pharmacobezoar formed from Vegetamine A® tablet ingestion. Acute Med Surg. 2014 Jul 14;2(1):60-63. doi: 10.1002/ams2.58. eCollection 2015 Jan. PMID: 29123693; PMCID: PMC5667188.
Copy Download .nbib Format: NLM
Share it on

Acute Med Surg. 2014 Jul 14;2(1):60-63. doi: 10.1002/ams2.58. eCollection 2015 Jan.

An unexpected prolonged coma due to a pharmacobezoar formed from Vegetamine A® tablet ingestion.

Acute medicine & surgery

Chie Sato, Yoshito Kamijo

Affiliations

  1. Department of Emergency and Critical Care Medicine, School of Medicine Kitasato University Sagamihara Japan.

PMID: 29123693 PMCID: PMC5667188 DOI: 10.1002/ams2.58

Abstract

CASE: A 49-year-old man ingested massive quantities of Vegetamine A® tablets that contain two anticholinergic agents in addition to phenobarbital. The patient remained in an unexpectedly prolonged coma 4 days post-hospitalization. An acute gastroscopy revealed a pinkish-white pharmacobezoar on the lesser curvature of the stomach, which was extracted using a net. Direct hemoperfusion and treatment with multiple-dose activated charcoal was then initiated. Phenobarbital serum concentrations eventually decreased, resulting in complete recovery of the patient.

OUTCOME: On day 30, the patient was transferred to the Psychiatric Department.

CONCLUSION: An intragastric pharmacobezoar should be suspected in patients with promoted and prolonged toxicity or if high serum concentrations of agents indicate their continuous absorption.

Keywords: Gastroscopy; Vegetamine A® tablet; pharmacobezoar; phenobarbital

References

  1. Br Med J (Clin Res Ed). 1986 Nov 1;293(6555):1143 - PubMed
  2. J Toxicol Clin Toxicol. 2000;38(5):477-82 - PubMed
  3. Clin Toxicol (Phila). 2008 Apr;46(4):317-9 - PubMed
  4. Ann Pharmacother. 1998 Sep;32(9):940-6 - PubMed
  5. Clin Toxicol (Phila). 2007 Sep;45(6):735 - PubMed
  6. Clin Toxicol (Phila). 2008 Nov;46(9):913-5 - PubMed

Publication Types