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Rheum Dis Clin North Am. 2018 Feb;44(1):165-175. doi: 10.1016/j.rdc.2017.09.011.

Gastrointestinal and Hepatic Disease in Systemic Lupus Erythematosus.

Rheumatic diseases clinics of North America

Brian N Brewer, Diane L Kamen

Affiliations

  1. Department of Internal Medicine, Augusta University-University of Georgia, 108 Spear Road, Athens, GA 30602, USA.
  2. Division of Rheumatology and Immunology, Medical University of South Carolina, 96 Jonathan Lucas Street, Suite 916 e, Charleston, SC 29425, USA. Electronic address: [email protected].

PMID: 29149925 PMCID: PMC5796428 DOI: 10.1016/j.rdc.2017.09.011

Abstract

Gastrointestinal (GI) symptoms are common among patients with systemic lupus erythematosus (SLE), although only rarely are they caused by active organ system involvement from SLE itself. Rapid diagnosis and appropriate treatment of lupus enteritis and other GI manifestations of SLE are critical, because of the potential for organ and life-threatening complications. The 3 main variants of lupus enteritis are lupus mesenteric vasculitis, intestinal pseudo-obstruction, and protein-losing enteropathy. These GI manifestations and others in patients with SLE are reviewed here.

Copyright © 2017 Elsevier Inc. All rights reserved.

Keywords: Enteral vasculitis; Intestinal pseudo-obstruction; Lupus enteritis; Protein-losing enteropathy

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