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Tarui T, Yoshikawa K, Miyakuni Y, et al. Independent risk factors for a complicated hospital course in intensive care unit overdose patients. Acute Med Surg. 2014;2(2):98-104doi: 10.1002/ams2.77.
Tarui, T., Yoshikawa, K., Miyakuni, Y., Kaita, Y., Tamada, N., Matsuda, T., Miyauchi, H., Yamada, K., Matsuda, T., & Yamaguchi, Y. (2015). Independent risk factors for a complicated hospital course in intensive care unit overdose patients. Acute medicine & surgery, 2(2), 98-104. https://doi.org/10.1002/ams2.77
Tarui, Takehiko, et al. "Independent risk factors for a complicated hospital course in intensive care unit overdose patients." Acute medicine & surgery vol. 2,2 (2015): 98-104. doi: https://doi.org/10.1002/ams2.77
Tarui T, Yoshikawa K, Miyakuni Y, Kaita Y, Tamada N, Matsuda T, Miyauchi H, Yamada K, Matsuda T, Yamaguchi Y. Independent risk factors for a complicated hospital course in intensive care unit overdose patients. Acute Med Surg. 2014 Sep 17;2(2):98-104. doi: 10.1002/ams2.77. eCollection 2015 Apr. PMID: 29123701; PMCID: PMC5667207.
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Acute Med Surg. 2014 Sep 17;2(2):98-104. doi: 10.1002/ams2.77. eCollection 2015 Apr.

Independent risk factors for a complicated hospital course in intensive care unit overdose patients.

Acute medicine & surgery

Takehiko Tarui, Kei Yoshikawa, Yasuhiko Miyakuni, Yasuhiko Kaita, Nao Tamada, Taketo Matsuda, Hiroshi Miyauchi, Kenji Yamada, Takeaki Matsuda, Yoshihiro Yamaguchi

Affiliations

  1. Department of Traumatology and Critical Care Medicine Kyorin University School of Medicine Tokyo Japan.

PMID: 29123701 PMCID: PMC5667207 DOI: 10.1002/ams2.77

Abstract

AIM: The purpose of the present study was to identify risk factors associated with a complicated hospital course in overdose patients admitted to the intensive care unit.

METHODS: A total of 335 overdose patients were retrospectively studied in the surgical and medical intensive care unit of an academic tertiary hospital. Factors possibly associated with a complicated hospital course were evaluated. Complicated hospital course was defined as the occurrence of pneumonia, rhabdomyolysis, decubitus ulcer, nerve palsy, prolonged intubation, prolonged hospitalization, or death.

RESULTS: Of the 335 overdose patients, 93 (27.8%) had a complicated hospital course. Complicated hospital course was found to be associated with a high number of ingested pills (median, 135 [interquartile range, 78-240] versus 84 [53-134] tablets,

CONCLUSION: The total number of ingested pills, admission Glasgow Coma Scale score, and serum lactate level on admission are predictive of a complicated hospital course in overdose patients admitted to the intensive care unit.

Keywords: Complications; drug overdose; lactate; toxicology/poisoning; triage

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