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Oncotarget. 2017 Jun 16;8(44):76099-76107. doi: 10.18632/oncotarget.18546. eCollection 2017 Sep 29.

The correlation of neutrophil-to-lymphocyte ratio with the presence and activity of myasthenia gravis.

Oncotarget

De-Hao Yang, Mei-Zi Qian, Mao-Mao Wei, Jia Li, Meng-Meng Yu, Xue-Mian Lu, Hong Yang, Hai Lin, Xiang Li, Jun-Yan Zhu, Xu Zhang

Affiliations

  1. Department of Endocrinology, The Third Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China.
  2. Department of Anesthesiology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China.
  3. School of the First Clinical Medical Sciences, Wenzhou Medical University, Wenzhou 325000, China.
  4. Department of Neurology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China.
  5. Institute of Diagnostic and Interventional Radiology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai 200233, China.

PMID: 29100295 PMCID: PMC5652689 DOI: 10.18632/oncotarget.18546

Abstract

Though the pathogenesis of myasthenia gravis (MG) is not fully understood, the role of inflammation has been well appreciated in the development of MG. We aimed to investigate the role of neutrophil-to-lymphocyte ratio (NLR) in MG patients and the relationship between the NLR and the activity of the disease. A total number of 172 MG patients and 207 healthy controls (HC) were enrolled in this study. The MG patients were divided into tertiles according to NLR (low NLR < 1.58,

Keywords: MGFA; disease activity; myasthenia gravis; neutrophil-to-lymphocyte ratio; new predictor

Conflict of interest statement

CONFLICTS OF INTEREST The authors report no declarations of interest.

References

  1. J Dermatol. 2016 Mar;43(3):305-10 - PubMed
  2. Bratisl Lek Listy. 2015;116(4):213-7 - PubMed
  3. Int J Epidemiol. 1990 Dec;19(4):889-93 - PubMed
  4. Laryngoscope. 2015 Jul;125(7):E257-61 - PubMed
  5. Biochem Pharmacol. 2015 Oct 15;97(4):609-619 - PubMed
  6. Diabetes Technol Ther. 2013 Nov;15(11):942-7 - PubMed
  7. J Autoimmun. 2014 Aug;52:53-63 - PubMed
  8. Clin Rev Allergy Immunol. 2017 Feb;52(1):108-124 - PubMed
  9. Oncotarget. 2016 Feb 16;7(7):7550-62 - PubMed
  10. BMC Cancer. 2016 Mar 05;16:185 - PubMed
  11. Clin Exp Nephrol. 2013 Aug;17 (4):532-40 - PubMed
  12. J Clin Lab Anal. 2016 Sep;30(5):597-601 - PubMed
  13. Oncotarget. 2016 Aug 9;7(32):50963-50971 - PubMed
  14. J Autoimmun. 2011 Mar;36(2):135-41 - PubMed
  15. Mediators Inflamm. 2016;2016:8191254 - PubMed
  16. Int J Neurosci. 2016 Aug;126(8):700-6 - PubMed
  17. J Atheroscler Thromb. 2014;21(12):1271-82 - PubMed
  18. PLoS One. 2016 May 20;11(5):e0156101 - PubMed
  19. Immunity. 2011 Dec 23;35(6):986-96 - PubMed
  20. Kaohsiung J Med Sci. 2015 Dec;31(12 ):626-31 - PubMed
  21. Am J Cardiol. 2008 Mar 15;101(6):747-52 - PubMed
  22. Sci Rep. 2016 May 13;6:25886 - PubMed
  23. Am Heart J. 2007 Nov;154(5):995-1002 - PubMed
  24. N Engl J Med. 1994 Jun 23;330(25):1797-810 - PubMed
  25. Autoimmun Rev. 2013 Jul;12(9):863-74 - PubMed
  26. Neurology. 1991 Sep;41(9):1497-504 - PubMed
  27. Ann Thorac Surg. 2000 Jul;70(1):327-34 - PubMed

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