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Oncotarget. 2017 May 23;8(45):79356-79365. doi: 10.18632/oncotarget.18119. eCollection 2017 Oct 03.

Utility of endoscopic ultrasound-guided fine-needle aspiration of regional lymph nodes that are proximal to and far from the primary distal esophageal carcinoma.

Oncotarget

Yusuke Shimodaira, Rebecca S Slack, Kazuto Harada, Manoop S Bhutani, Elena Elimova, Gregg A Staerkel, Nour Sneige, Jeremy Erasmus, Hironori Shiozaki, Nikolaos Charalampakis, Venkatram Planjery, Dilsa Mizrak Kaya, Fatemeh G Amlashi, Mariela A Blum, Heath D Skinner, Bruce D Minsky, Dipen M Maru, Wayne L Hofstetter, Stephen G Swisher, Jeannette E Mares, Jane E Rogers, Quan D Lin, William A Ross, Brian Weston, Jeffrey H Lee, Jaffer A Ajani

Affiliations

  1. Department of Gastrointestinal Medical Oncology, University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA.
  2. Department of Biostatistics, University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA.
  3. Department of Gastroenterology, University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA.
  4. Department of Anatomic Pathology, University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA.
  5. Department of Pathology, University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA.
  6. Department of Diagnostic Radiology, University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA.
  7. Department of Radiation Oncology, University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA.
  8. Department of Thoracic and Cardiovascular Surgery, University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA.
  9. Department of Pharmacy, University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA.

PMID: 29108314 PMCID: PMC5668047 DOI: 10.18632/oncotarget.18119

Abstract

Implications of assessing the proximal and far para-tracheal or sub-carinal nodes (para-tracheal [PTN] or sub-carinal [SCN]) associated with lower primary esophageal carcinomas (ECs) are unclear. To evaluate the value of endoscopic ultrasound guided fine-needle aspiration (EUS-FNA) for PTN and SCN, we analyzed results by positron emission tomography (PET) avidity, 4 EUS node malignancy features, and EUS-FNA results in all patients with Siewert's I or II EC. Of 133 patients (PTN,

Keywords: endoscopic ultrasound; esophageal carcinoma; fine-needle aspiration; positron emission tomography; upper mediastinal lymph nodes

Conflict of interest statement

CONFLICTS OF INTEREST The authors have declared no conflicts of interest.

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