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Tang J, Kong D, Bu L, et al. Surgical management for follicular variant of papillary thyroid carcinoma. Oncotarget. 2017;8(45):79507-79516doi: 10.18632/oncotarget.18525.
Tang, J., Kong, D., Bu, L., & Wu, G. (2017). Surgical management for follicular variant of papillary thyroid carcinoma. Oncotarget, 8(45), 79507-79516. https://doi.org/10.18632/oncotarget.18525
Tang, Jianing, et al. "Surgical management for follicular variant of papillary thyroid carcinoma." Oncotarget vol. 8,45 (2017): 79507-79516. doi: https://doi.org/10.18632/oncotarget.18525
Tang J, Kong D, Bu L, Wu G. Surgical management for follicular variant of papillary thyroid carcinoma. Oncotarget. 2017 Jun 16;8(45):79507-79516. doi: 10.18632/oncotarget.18525. eCollection 2017 Oct 03. PMID: 29108330; PMCID: PMC5668063.
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Oncotarget. 2017 Jun 16;8(45):79507-79516. doi: 10.18632/oncotarget.18525. eCollection 2017 Oct 03.

Surgical management for follicular variant of papillary thyroid carcinoma.

Oncotarget

Jianing Tang, Deguang Kong, Lupin Bu, Gaosong Wu

Affiliations

  1. Department of Breast and Thyroid Surgery, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, P.R. China.
  2. Department of General Surgery, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, P.R. China.

PMID: 29108330 PMCID: PMC5668063 DOI: 10.18632/oncotarget.18525

Abstract

BACKGROUND AND AIMS: For most patients with follicular variant of papillary thyroid carcinoma (FVPTC), surgery is required, while the surgical management remains controversial. We aim to further understanding of treatment of FVPTC and to determine whether specific features could be identified for the decision of surgical strategy.

MATERIALS AND METHODS: Data were obtained from the Surveillance, Epidemiology, and End Results (SEER) Program database during 2003 and 2013. 26700 patients were eligible and stratified by tumor size or extension. Survival rates were compared using multivariate Cox proportional hazard regressions.

RESULTS: Of the total death of 1041, 136 patients died from thyroid cancer. Most patients (79.1%) underwent total thyroidectomy while only a little part of patients (8.2%) underwent lobectomy. Patients receiving radioisotopes had significantly better overall survival (OS) (HR = 0.659,

CONCLUSIONS: The results of our study revealed total thyroidectomy could benefit the survival for patients whose tumors > 2 cm with extrathyroidal extension, total thyroidectomy should be recommended for those patients. Lots of factors should be taken into consideration on the decision of surgical treatment.

Keywords: SEER; follicular variant of papillary thyroid carcinoma; surgery

Conflict of interest statement

CONFLICTS OF INTEREST The authors have no conflicts of interest to disclose.

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