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Pei G, Lv W, Li X, et al. Influence of SPK with Enteric Drainage on the Pancreatic Exocrine Function in Diabetic Patients with Uremia. Int J Endocrinol. 2017;2017:3709306doi: 10.1155/2017/3709306.
Pei, G., Lv, W., Li, X., Zhang, G., & Zhang, J. (2017). Influence of SPK with Enteric Drainage on the Pancreatic Exocrine Function in Diabetic Patients with Uremia. International journal of endocrinology, 20173709306. https://doi.org/10.1155/2017/3709306
Pei, Guanghui, et al. "Influence of SPK with Enteric Drainage on the Pancreatic Exocrine Function in Diabetic Patients with Uremia." International journal of endocrinology vol. 2017 (2017): 3709306. doi: https://doi.org/10.1155/2017/3709306
Pei G, Lv W, Li X, Zhang G, Zhang J. Influence of SPK with Enteric Drainage on the Pancreatic Exocrine Function in Diabetic Patients with Uremia. Int J Endocrinol. 2017;2017:3709306. doi: 10.1155/2017/3709306. Epub 2017 Aug 24. PMID: 29138633; PMCID: PMC5613707.
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Int J Endocrinol. 2017;2017:3709306. doi: 10.1155/2017/3709306. Epub 2017 Aug 24.

Influence of SPK with Enteric Drainage on the Pancreatic Exocrine Function in Diabetic Patients with Uremia.

International journal of endocrinology

Guanghui Pei, Wu Lv, Xiaohang Li, Guoqing Zhang, Jialin Zhang

Affiliations

  1. Department of Hepatobiliary and Transplantation Surgery, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning Province, China.
  2. Department of Organ Transplantation, Tianjin First Central Hospital, Tianjin, China.
  3. Department of General Surgery, Liaoning Cancer Hospital and Institute, Shenyang, China.

PMID: 29138633 PMCID: PMC5613707 DOI: 10.1155/2017/3709306

Abstract

OBJECTIVE: This study aimed to determine the use of fecal elastase in evaluating the effect of simultaneous pancreas-kidney transplantation with enteric drainage on the pancreatic exocrine function of diabetic patients with uremia.

METHODS: A total of 19 patients with simultaneous pancreas-kidney transplantation (SPK) with enteric drainage, 31 diabetic patients with uremia (chronic renal failure (CRF)), 22 diabetic patients with uremia who underwent renal transplantation (RT), and 20 normal individuals (CON) were included in the study. Pancreatic exocrine insufficiency was determined using fecal elastase. Results. The fecal pancreatic elastase level in SPK patients with enteric drainage was 479 

CONCLUSIONS: The present study indicated that SPK with enteric drainage improves pancreatic endocrine and exocrine functions. Fecal elastase may be a clinically relevant means to determine the therapeutic effects.

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