Display options
Share it on

Curr Oral Health Rep. 2017 Sep;4(3):215-227. doi: 10.1007/s40496-017-0146-y. Epub 2017 Jul 10.

Recent Advances in Adhesive Bonding - The Role of Biomolecules, Nanocompounds, and Bonding Strategies in Enhancing Resin Bonding to Dental Substrates.

Current oral health reports

Eliseu A Münchow, Marco C Bottino

Affiliations

  1. Department of Dentistry, Health Science Institute, Federal University of Juiz de Fora, Governador Valadares, MG 35010, Brazil.
  2. Department of Biomedical and Applied Sciences, Division of Dental Biomaterials, Indiana University School of Dentistry, Indianapolis, IN 46202, USA.

PMID: 29177123 PMCID: PMC5697773 DOI: 10.1007/s40496-017-0146-y

Abstract

PURPOSE OF REVIEW: To present an overview on the main agents (i.e., biomolecules and nanocompounds) and/or strategies currently available to amplify or stabilize resin-dentin bonding.

RECENT FINDINGS: According to studies retrieved for full text reading (2014-2017), there are currently six major strategies available to overcome resin-dentin bond degradation: (i) use of collagen crosslinking agents, which may form stable covalent bonds with collagen fibrils, thus strengthening the hybrid layer; (ii) use of antioxidants, which may allow further polymerization reactions over time; (iii) use of protease inhibitors, which may inhibit or inactivate metalloproteinases; (iv) modification of the bonding procedure, which may be performed by using the ethanol wet-bonding technique or by applying an additional adhesive (hydrophobic) coating, thereby strengthening the hybrid layer; (v) laser treatment of the substrate prior to bonding, which may cause specific topographic changes in the surface of dental substrates, increasing bonding efficacy; and (vi) reinforcement of the resin matrix with inorganic fillers and/or remineralizing agents, which may positively enhance physico-mechanical properties of the hybrid layer.

SUMMARY: With the present review, we contributed to the better understanding of adhesion concepts and mechanisms of resin-dentin bond degradation, showing the current prospects available to solve that problematic. Also, adhesively-bonded restorations may be benefited by the use of some biomolecules, nanocompounds or alternative bonding strategies in order to minimize bond strength degradation.

Keywords: Collagen; Crosslinking Agents; Dentin; Dentin-Bonding; Matrix Metalloproteinase Inhibitors; Resins

Conflict of interest statement

Conflict of Interest The authors declare that they have no conflict of interest.

References

  1. Crit Rev Oral Biol Med. 2002;13(3):238-75 - PubMed
  2. J Dent. 2010 May;38(5):431-6 - PubMed
  3. J Biomed Mater Res B Appl Biomater. 2008 Aug;86(2):330-4 - PubMed
  4. J Dent Res. 2013 Aug;92(8):746-52 - PubMed
  5. Photomed Laser Surg. 2014 Sep;32(9):495-9 - PubMed
  6. J Dent Res. 2011 Aug;90(8):953-68 - PubMed
  7. Dent Mater. 2017 Mar;33(3):309-320 - PubMed
  8. Int J Mol Sci. 2014 May 20;15(5):8998-9015 - PubMed
  9. J Dent. 2013 Apr;41(4):321-7 - PubMed
  10. Eur J Oral Sci. 2015 Apr;123(2):102-7 - PubMed
  11. J Dent Res. 2001 Jun;80(6):1545-9 - PubMed
  12. Acta Biomater. 2010 Dec;6(12):4539-46 - PubMed
  13. Oper Dent. 2011 Nov-Dec;36(6):649-60 - PubMed
  14. J Contemp Dent Pract. 2015 Jul 01;16(7):547-53 - PubMed
  15. J Contemp Dent Pract. 2014 Jul 01;15(4):385-91 - PubMed
  16. Arch Oral Biol. 2007 Feb;52(2):121-7 - PubMed
  17. Biomaterials. 2007 Sep;28(26):3757-85 - PubMed
  18. Dent Res J (Isfahan). 2016 Mar-Apr;13(2):174-80 - PubMed
  19. J Dent Res. 2014 Dec;93(12):1270-6 - PubMed
  20. Dent Mater. 2013 Oct;29(10):999-1011 - PubMed
  21. Oper Dent. 2014 Sep-Oct;39(5):489-99 - PubMed
  22. J Endod. 2010 Mar;36(3):475-81 - PubMed
  23. J Dent Res. 2014 Mar;93(3):263-8 - PubMed
  24. Dent Mater. 2013 Oct;29(10):1040-7 - PubMed
  25. Braz Dent J. 2016 Jul-Aug;27(4):446-51 - PubMed
  26. Circ Res. 2003 May 2;92(8):827-39 - PubMed
  27. Dent Mater. 2009 Nov;25(11):1383-91 - PubMed
  28. Clin Oral Investig. 2015 Nov;19(8):1905-12 - PubMed
  29. Oper Dent. 2014 Mar-Apr;39(2):152-8 - PubMed
  30. J Adhes Dent. 2013 Oct;15(5):413-22 - PubMed
  31. Lancet. 1995 Sep 2;346(8975):645-6 - PubMed
  32. J Conserv Dent. 2016 Nov-Dec;19(6):555-559 - PubMed
  33. J Dent (Shiraz). 2015 Jun;16(2):68-74 - PubMed
  34. J Dent. 2015 Nov;43(11):1316-22 - PubMed
  35. Dent Mater. 2010 Oct;26(10):968-73 - PubMed
  36. J Dent Res. 2013 Jan;92(1):87-91 - PubMed
  37. Aust Endod J. 2009 Dec;35(3):131-9 - PubMed
  38. Acta Biomater. 2017 Apr 15;53:585-597 - PubMed
  39. Ann Med. 2006;38(5):306-21 - PubMed
  40. J Dent. 2011 Jan;39(1):40-7 - PubMed
  41. Eur J Oral Sci. 2017 Feb;125(1):63-71 - PubMed
  42. Dent Mater. 2006 Mar;22(3):211-22 - PubMed
  43. J Dent. 2011 Feb;39(2):148-53 - PubMed
  44. J Appl Oral Sci. 2016 May-Jun;24(3):211-7 - PubMed
  45. Biomaterials. 2008 Nov;29(33):4367-73 - PubMed
  46. J Dent Res. 2005 Aug;84(8):741-6 - PubMed
  47. J Conserv Dent. 2016 Nov-Dec;19(6):501-509 - PubMed
  48. Eur J Oral Sci. 2010 Oct;118(5):494-501 - PubMed
  49. Int J Clin Exp Med. 2015 Jul 15;8(7):10793-803 - PubMed
  50. J Dent. 2016 Feb;45:7-13 - PubMed
  51. J Lasers Med Sci. 2016 Summer;7(3):152-158 - PubMed
  52. J Dent. 2014 May;42(5):595-602 - PubMed
  53. Eur J Oral Sci. 2015 Apr;123(2):108-15 - PubMed
  54. J Dent Res. 2005 Apr;84(4):355-9 - PubMed
  55. Cardiovasc Res. 2006 Feb 15;69(3):562-73 - PubMed
  56. Dent Mater. 2016 Feb;32(2):e41-53 - PubMed
  57. J Adhes Dent. 2016;18(1):35-42 - PubMed
  58. J Dent Res. 2012 Feb;91(2):192-6 - PubMed
  59. J Endod. 2015 Oct;41(10 ):1667-71 - PubMed
  60. Dent Mater. 2010 Aug;26(8):771-8 - PubMed
  61. J Adhes Dent. 2015 Dec;17(6):499-504 - PubMed
  62. Shika Zairyo Kikai. 1989 Nov;8(6):890-5 - PubMed
  63. J Dent. 2013 Nov;41(11):1101-8 - PubMed
  64. Dent Mater. 2011 Jan;27(1):1-16 - PubMed
  65. Eur J Oral Sci. 2014 Dec;122(6):417-23 - PubMed
  66. J Dent Res. 2009 Sep;88(9):807-11 - PubMed
  67. J Dent Res. 2014 Aug;93(8):733-43 - PubMed
  68. J Conserv Dent. 2015 Sep-Oct;18(5):360-3 - PubMed
  69. J Dent Res. 2005 Feb;84(2):118-32 - PubMed
  70. Arch Oral Biol. 2000 Sep;45(9):757-65 - PubMed
  71. J Dent. 2009 Oct;37(10):807-12 - PubMed
  72. J Dent. 2012 Jun;40(6):458-66 - PubMed
  73. J Adhes Dent. 2012 Aug;14 (4):355-62 - PubMed
  74. Curr Opin Rheumatol. 1996 May;8(3):238-47 - PubMed
  75. J Dent. 2012 Mar;40(3):173-80 - PubMed
  76. J Endod. 2012 Sep;38(9):1227-32 - PubMed
  77. J Dent Res. 2007 Jun;86(6):529-33 - PubMed
  78. Oper Dent. 2007 Mar-Apr;32(2):107-11 - PubMed
  79. J Adhes Dent. 2015 Feb;17(1):35-44 - PubMed
  80. Drug Resist Updat. 2004 Jun;7(3):195-208 - PubMed
  81. Dent Mater. 2016 Oct;32(10 ):1248-55 - PubMed
  82. Dent Mater. 2016 Jul;32(7):940-50 - PubMed
  83. Dent Mater. 2013 Nov;29(11):1158-65 - PubMed
  84. Biomacromolecules. 2014 Dec 8;15(12):4606-13 - PubMed
  85. Dent Mater. 2015 Jul;31(7):759-77 - PubMed
  86. Eur J Prosthodont Restor Dent. 2014 Mar;22(1):29-34 - PubMed
  87. J Dent. 2011 Mar;39(3):231-7 - PubMed
  88. J Dent. 2009 Feb;37(2):108-14 - PubMed
  89. J Dent Res. 2012 Apr;91(4):420-5 - PubMed
  90. Dent Mater. 2011 Jan;27(1):17-28 - PubMed
  91. Int J Oral Sci. 2009 Dec;1(4):163-76 - PubMed
  92. J Adhes Dent. 2016;18(4):349-54 - PubMed
  93. J Biomed Mater Res B Appl Biomater. 2010 Jul;94(1):250-5 - PubMed
  94. Oper Dent. 2016 Sep-Oct;41(5):511-519 - PubMed
  95. Dent Mater. 2015 Oct;31(10 ):e236-46 - PubMed
  96. J Dent Res. 2007 May;86(5):436-40 - PubMed

Publication Types

Grant support