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Oncotarget. 2017 Jul 19;8(53):90808-90824. doi: 10.18632/oncotarget.19385. eCollection 2017 Oct 31.

VEGF.

Oncotarget

Julien Broséus, Samia Mourah, Gérard Ramstein, Sophie Bernard, Nicolas Mounier, Wendy Cuccuini, Philippe Gaulard, Christian Gisselbrecht, Josette Brière, Rémi Houlgatte, Catherine Thieblemont

Affiliations

  1. Inserm U954, Faculty of Medicine, University of Lorraine, Nancy, France.
  2. University Hospital of Nancy, Hematology Laboratory, Nancy, France.
  3. Paris Diderot University, Sorbonne Paris Cité, Paris, France.
  4. APHP, Saint Louis University Hospital, Pharmacology-Biologic Laboratory, Paris, France.
  5. Inserm UMRS 976, France.
  6. LS2N - DUKe, University of Nantes, Nantes, France.
  7. APHP, Saint-Louis University Hospital, Hemato-Oncology, Paris, France.
  8. University Hospital of L'archet, Nice, France.
  9. APHP, Saint-Louis University Hospital, Hematology Laboratory, Paris, France.
  10. Department of Pathology, APHP, Henri Mondor University Hospital, Creteil, France.
  11. Inserm U955, University Paris-Est, Créteil, France.
  12. Lymphoma Study Association, Pierre-Bénite, France.
  13. Department of Pathology, APHP, Saint-Louis University Hospital, Paris, France.
  14. University Hospital of Nancy, DRCI, Nancy, France.

PMID: 29207605 PMCID: PMC5710886 DOI: 10.18632/oncotarget.19385

Abstract

Tumor microenvironment including endothelial and immune cells plays a crucial role in tumor progression and has been shown to dramatically influence cancer survival. In this study, we investigated the clinical relevance of the gene expression of key mediators of angiogenesis, VEGF isoforms 121, 165, and 189, and their receptors (VEGFR-1 and R-2) in a cohort of patients (

Keywords: ABC; angiogenesis; cancer; immune response; like DLBCL

Conflict of interest statement

CONFLICTS OF INTEREST Professor C. Gisselbrecht: Research funding by Roche. The other authors declare no competing financial interests.

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