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Oncotarget. 2017 Jul 08;8(51):88259-88275. doi: 10.18632/oncotarget.19111. eCollection 2017 Oct 24.

Regulation of S-formylglutathione hydrolase by the anti-aging gene klotho.

Oncotarget

Yuechi Xu, Zhongjie Sun

Affiliations

  1. Department of Physiology, College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.

PMID: 29179433 PMCID: PMC5687603 DOI: 10.18632/oncotarget.19111

Abstract

Klotho is an aging-suppressor gene. The purpose of this study is to investigate the binding sites (receptors) and function of short-form Klotho (Skl). We showed that Skl physically bound to multiple proteins. We found physical and functional interactions between Skl and

Keywords: GSH; Gerotarget; S-formylglutathione hydrolase; binding; klotho; receptor

Conflict of interest statement

CONFLICTS OF INTEREST There is no competing financial interest.

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