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Chiba N, Shimazu M, Takano K, et al. Predicting hepatic failure with a new diagnostic technique by preoperative liver scintigraphy and computed tomography: a pilot study in 123 patients undergoing liver resection. Patient Saf Surg. 2017;11:29doi: 10.1186/s13037-017-0143-z.
Chiba, N., Shimazu, M., Takano, K., Oshima, G., Tomita, K., Sano, T., Okihara, M., Ozawa, Y., Hikita, K., Gunji, T., Abe, Y., Koizumi, K., & Kawachi, S. (2017). Predicting hepatic failure with a new diagnostic technique by preoperative liver scintigraphy and computed tomography: a pilot study in 123 patients undergoing liver resection. Patient safety in surgery, 1129. https://doi.org/10.1186/s13037-017-0143-z
Chiba, Naokazu, et al. "Predicting hepatic failure with a new diagnostic technique by preoperative liver scintigraphy and computed tomography: a pilot study in 123 patients undergoing liver resection." Patient safety in surgery vol. 11 (2017): 29. doi: https://doi.org/10.1186/s13037-017-0143-z
Chiba N, Shimazu M, Takano K, Oshima G, Tomita K, Sano T, Okihara M, Ozawa Y, Hikita K, Gunji T, Abe Y, Koizumi K, Kawachi S. Predicting hepatic failure with a new diagnostic technique by preoperative liver scintigraphy and computed tomography: a pilot study in 123 patients undergoing liver resection. Patient Saf Surg. 2017 Dec 18;11:29. doi: 10.1186/s13037-017-0143-z. eCollection 2017. PMID: 29270223; PMCID: PMC5735932.
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Patient Saf Surg. 2017 Dec 18;11:29. doi: 10.1186/s13037-017-0143-z. eCollection 2017.

Predicting hepatic failure with a new diagnostic technique by preoperative liver scintigraphy and computed tomography: a pilot study in 123 patients undergoing liver resection.

Patient safety in surgery

Naokazu Chiba, Motohide Shimazu, Kiminori Takano, Go Oshima, Koichi Tomita, Toru Sano, Masaaki Okihara, Yosuke Ozawa, Kosuke Hikita, Takahiro Gunji, Yuta Abe, Kiyoshi Koizumi, Shigeyuki Kawachi

Affiliations

  1. Department of Digestive and Transplantation Surgery, Tokyo Medical University Hachioji Medical Center, Tokyo, Japan.
  2. 1163 Tatemachi, Hachioji, Tokyo 193-0998 Japan.
  3. Department of Surgery, Tama Kyuryo Hospital, Tokyo, Japan.
  4. Department of Surgery, Keio University school of Medicine, Tokyo, Japan.
  5. Department of Radiology, Tokyo Medical University Hachioji Medical Center, Tokyo, Japan.

PMID: 29270223 PMCID: PMC5735932 DOI: 10.1186/s13037-017-0143-z

Abstract

BACKGROUND: A novel index, total liver LU15, has been identified as a surrogate marker for liver function. We evaluated the ability of preoperative remnant liver LU15 values to predict postoperative hepatic failure.

METHODS: Preoperative risk factors for postoperative hepatic failure and remnant liver LU15 were evaluated in 123 patients undergoing liver resection for several diseases from September 1st, 2007 to December 1st, 2016. We calculated the remnant liver LU15 value from the total liver LU15 value and the functional remnant liver ratio. Risk factors for postoperative hepatic failure was determined by univariate and multivariate analysis.

RESULTS: Hepatic failure grade B/C developed postoperatively in six patients of seven patients within Makuuchi criteria / without criteria for remnant liver LU15. Operative time (

CONCLUSION: Based on the findings form this pilot study, it appears that patients with a remnant liver LU15 value of 13 or less may have a high risk of postoperative hepatic failure.

Keywords: 99mTc-labelled galactosyl human serum albumin liver scintigraphy; Hepatic failure; Remnant liver LU15

Conflict of interest statement

This research data was approved by Tokyo Medical University Hachioji Medical Center Ethics committee (Approval No. H175).This research data had consent of publications from all patents.The authors dec

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