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Hocker S, Rabinovitz HS, Oliviero M, et al. Reflectance confocal microscopy of an inverted follicular keratosis mimicking a squamous cell carcinoma. Dermatol Pract Concept. 2017;7(4):39-42doi: 10.5826/dpc.0704a09.
Hocker, S., Rabinovitz, H. S., Oliviero, M., Grant-Kels, J., & Scope, A. (2017). Reflectance confocal microscopy of an inverted follicular keratosis mimicking a squamous cell carcinoma. Dermatology practical & conceptual, 7(4), 39-42. https://doi.org/10.5826/dpc.0704a09
Hocker, Sarah, et al. "Reflectance confocal microscopy of an inverted follicular keratosis mimicking a squamous cell carcinoma." Dermatology practical & conceptual vol. 7,4 (2017): 39-42. doi: https://doi.org/10.5826/dpc.0704a09
Hocker S, Rabinovitz HS, Oliviero M, Grant-Kels J, Scope A. Reflectance confocal microscopy of an inverted follicular keratosis mimicking a squamous cell carcinoma. Dermatol Pract Concept. 2017 Oct 31;7(4):39-42. doi: 10.5826/dpc.0704a09. eCollection 2017 Oct. PMID: 29214108; PMCID: PMC5718125.
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Dermatol Pract Concept. 2017 Oct 31;7(4):39-42. doi: 10.5826/dpc.0704a09. eCollection 2017 Oct.

Reflectance confocal microscopy of an inverted follicular keratosis mimicking a squamous cell carcinoma.

Dermatology practical & conceptual

Sarah Hocker, Harold S Rabinovitz, Margaret Oliviero, Jane Grant-Kels, Alon Scope

Affiliations

  1. Skin and Cancer Associates, Plantation, FL, USA.
  2. Department of Dermatology, University of Miami Miller School of Medicine, Miami, FL, USA.
  3. Department of Dermatology, University of Connecticut, Farmington, CT, USA.
  4. Department of Dermatology, Sheba Medical Center and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

PMID: 29214108 PMCID: PMC5718125 DOI: 10.5826/dpc.0704a09

Abstract

Distinguishing between benign and malignant neoplasms of the skin is a daily challenge to dermatologists. With the use of a dermatoscope and other imaging devices, the diagnosis is often more precise. The confocal microscope is a device that uses a near-infrared laser to perform noninvasive imaging of the skin. The benefit is that the images immediately provide additional, cellular-level information that can assist in diagnosis. However, lesions may share overlapping characteristics on confocal microscopy, and hence, benign lesions can still display confocal features concerning for a cancerous process, justifying a biopsy. Here, we present a case of an inverted follicular keratosis imitating a squamous cell carcinoma on confocal microscopy.

Keywords: dermoscopy; inverted follicular keratosis; reflectance confocal microscopy; squamous cell carcinoma

Conflict of interest statement

Competing interests: Harold S. Rabinovitz, MD, and Margaret Oliviero, ARNP, MSN, are clinical investigators for Caliber I.D.

References

  1. J Clin Pathol. 1975 Jun;28(6):465-71 - PubMed
  2. Dermatology. 2013;227(1):62-6 - PubMed
  3. Am J Dermatopathol. 1983 Oct;5(5):427-42 - PubMed

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