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Front Pediatr. 2017 Nov 14;5:223. doi: 10.3389/fped.2017.00223. eCollection 2017.

Sudden Infant Death Syndrome, Infection, Prone Sleep Position, and Vagal Neuroimmunology.

Frontiers in pediatrics

Paul Nathan Goldwater

Affiliations

  1. Discipline of Paediatrics, School of Paediatrics and Reproductive Health, University of Adelaide, North Adelaide, SA, Australia.

PMID: 29184885 PMCID: PMC5694444 DOI: 10.3389/fped.2017.00223

Abstract

Recent findings suggest that infection (and sepsis) stand alone as the only plausible mechanism of causation of sudden infant death syndrome (SIDS) and accordingly achieves congruence with all clinicopathological and epidemiological findings. This review examines the role of infection in the pathogenesis of SIDS in the context of the major risk factor of prone sleep position. The study explores how sleep position could interact with the immune system and inflammatory response

Keywords: infection; neuroimmunology; prone sleep position; sudden infant death syndrome; vagus

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