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Parasar P, Ozcan P, Terry KL. Endometriosis: Epidemiology, Diagnosis and Clinical Management. Curr Obstet Gynecol Rep. 2017;6(1):34-41doi: 10.1007/s13669-017-0187-1.
Parasar, P., Ozcan, P., & Terry, K. L. (2017). Endometriosis: Epidemiology, Diagnosis and Clinical Management. Current obstetrics and gynecology reports, 6(1), 34-41. https://doi.org/10.1007/s13669-017-0187-1
Parasar, Parveen, et al. "Endometriosis: Epidemiology, Diagnosis and Clinical Management." Current obstetrics and gynecology reports vol. 6,1 (2017): 34-41. doi: https://doi.org/10.1007/s13669-017-0187-1
Parasar P, Ozcan P, Terry KL. Endometriosis: Epidemiology, Diagnosis and Clinical Management. Curr Obstet Gynecol Rep. 2017 Mar;6(1):34-41. doi: 10.1007/s13669-017-0187-1. Epub 2017 Jan 27. PMID: 29276652; PMCID: PMC5737931.
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Curr Obstet Gynecol Rep. 2017 Mar;6(1):34-41. doi: 10.1007/s13669-017-0187-1. Epub 2017 Jan 27.

Endometriosis: Epidemiology, Diagnosis and Clinical Management.

Current obstetrics and gynecology reports

Parveen Parasar, Pinar Ozcan, Kathryn L Terry

Affiliations

  1. Boston Center for Endometriosis, Boston Children's and Brigham and Women's Hospitals, 333 and 221 Longwood Avenue, Boston, MA 02115, USA.
  2. Center for Infertility and Reproductive Surgery, Department of Obstetrics, Gynecology, and Reproductive Biology, Brigham and Women's Hospital and Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA.
  3. Obstetrics and Gynecology Epidemiology Center, Brigham and Women's Hospital and Harvard Medical School, 221 Longwood Avenue, Boston, MA 02115, USA.
  4. Harvard T.H. Chan School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA.

PMID: 29276652 PMCID: PMC5737931 DOI: 10.1007/s13669-017-0187-1

Abstract

PURPOSE OF REVIEW: Endometriosis is a disease of adolescents and reproductive-aged women characterized by the presence of endometrial tissue outside the uterine cavity and commonly associated with chronic pelvic pain and infertility. Here we review the epidemiology of endometriosis as well as potential biomarkers for detection and with the goal of highlighting risk factors that could be used in combination with biomarkers to identify and treat women with endometriosis earlier..

RECENT FINDINGS: Early age at menarche, shorter menstrual length, and taller height are associated with a higher risk of endometriosis while parity, higher body mass index (BMI) and smoking are associated with decreased risk. Endometriosis often presents as infertility or continued pelvic pain despite treatment with analgesics and cyclic oral contraceptive pills.

SUMMARY: Despite a range of symptoms, diagnosis of endometriosis is often delayed due to lack of non-invasive, definitive and consistent biomarkers for diagnosis of endometriosis. Hormone therapy and analgesics are used for treatment of symptomatic endometriosis. However, the efficacy of these treatments are limited as endometriosis often recurs. In this review, we describe potential diagnostic biomarkers and risk factors that may be used as early non-invasive

Keywords: Biomarkers; Endometriosis; Infertility; Management; Pain

Conflict of interest statement

Conflict of Interest Parveen Parasar, Pinar Ozcan, and Kathryn L. Terry declare that they have no conflict of interest.

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