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Korean J Pediatr. 2017 Dec;60(12):385-389. doi: 10.3345/kjp.2017.60.12.385. Epub 2017 Dec 22.

Does anaesthesia in mothers during delivery affect bilirubin levels in their neonates?.

Korean journal of pediatrics

Zeinab A El-Kabbany, Nadin N Toaima, Tamer N Toaima, Mona Y Gamal El-Din

Affiliations

  1. Department of Pediatrics, Faculty of Medicine, Ain-Shams University, Cairo, Egypt.
  2. Department of Anaesthesiology and Intensive Care Unit, Faculty of Medicine, Ain-Shams University, Cairo, Egypt.
  3. Ministry of Health Hospital, Cairo, Egypt.

PMID: 29302262 PMCID: PMC5752638 DOI: 10.3345/kjp.2017.60.12.385

Abstract

PURPOSE: This study aimed to assess whether different anesthetic techniques and oxytocin use applied during delivery affect transcutaneous bilirubin levels during the first 24 hours in neonates.

METHODS: A total of 1,044 neonates delivered by either caesarian section (C/S) or normal vaginal delivery (NVD) were included in the study. They were classified into 5 groups as follows: group 1: born by C/S using general anesthesia, group 2: C/S using spinal anaesthesia, group 3: C/S using general anesthesia after failed spinal block, group 4: by NVD without anesthesia, and group 5: oxytocin-induced vaginal delivery without anesthesia. Transcutaneous total bilirubin levels (TBLs) were measured during the first 24 hours and on the fifth and eighth days of life and the levels in different groups were compared.

RESULTS: The TBLs were significantly higher in neonates delivered by C/S using general anesthesia rather than spinal anesthesia (

CONCLUSIONS: C/S and general anesthesia adversely affect the bilirubin levels in neonates, and the use of oxytocin during vaginal delivery also increases TBLs in neonates.

Keywords: Anesthesia; Delivery; Hyperbilirubinemia; Jaundice; Neonates

Conflict of interest statement

Conflicts of interest: No potential conflict of interest relevant to this article was reported.

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