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Oncotarget. 2017 Sep 30;8(56):95896-95913. doi: 10.18632/oncotarget.21436. eCollection 2017 Nov 10.

TRPM8 is required for survival and radioresistance of glioblastoma cells.

Oncotarget

Dominik Klumpp, Stephanie C Frank, Lukas Klumpp, Efe C Sezgin, Marita Eckert, Lena Edalat, Martin Bastmeyer, Daniel Zips, Peter Ruth, Stephan M Huber

Affiliations

  1. Department of Radiation Oncology, University of Tübingen, Tübingen, Germany.
  2. Zoological Institute, Department of Cell- and Neurobiology, Karlsruhe Institute of Technology (KIT), Karlsruhe, Germany.
  3. Institute of Functional Interfaces, Karlsruhe Institute of Technology (KIT), Eggenstein-Leopoldshafen, Germany.
  4. Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany.
  5. University of Tübingen, Tübingen, Germany.
  6. Department of Pharmacology, Toxicology and Clinical Pharmacy, University of Tübingen, Tübingen, Germany.

PMID: 29221175 PMCID: PMC5707069 DOI: 10.18632/oncotarget.21436

Abstract

TRPM8 is a Ca

Keywords: Ca2+ signaling; TRPM8 channels; cell migration; glioblastoma; radioresistance

Conflict of interest statement

CONFLICTS OF INTEREST The authors declare no conflicts of interest.

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