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Davanzo J, Greiner RJ, Barbour M, et al. Radiation Necrosis Following Proton Beam Therapy in the Pediatric Population: a Case Series. Cureus. 2017;9(10):e1785doi: 10.7759/cureus.1785.
Davanzo, J., Greiner, R. J., Barbour, M., & Rizk, E. (2017). Radiation Necrosis Following Proton Beam Therapy in the Pediatric Population: a Case Series. Cureus, 9(10), e1785. https://doi.org/10.7759/cureus.1785
Davanzo, Justin, et al. "Radiation Necrosis Following Proton Beam Therapy in the Pediatric Population: a Case Series." Cureus vol. 9,10 (2017): e1785. doi: https://doi.org/10.7759/cureus.1785
Davanzo J, Greiner RJ, Barbour M, Rizk E. Radiation Necrosis Following Proton Beam Therapy in the Pediatric Population: a Case Series. Cureus. 2017 Oct 19;9(10):e1785. doi: 10.7759/cureus.1785. PMID: 29279811; PMCID: PMC5736167.
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Cureus. 2017 Oct 19;9(10):e1785. doi: 10.7759/cureus.1785.

Radiation Necrosis Following Proton Beam Therapy in the Pediatric Population: a Case Series.

Cureus

Justin Davanzo, Robert J Greiner, Mustafa Barbour, Elias Rizk

Affiliations

  1. Department of Neurosurgery, Penn State Milton S. Hershey Medical Center.
  2. Pediatric Oncology, Penn State Milton S. Hershey Medical Center.

PMID: 29279811 PMCID: PMC5736167 DOI: 10.7759/cureus.1785

Abstract

Radiation necrosis after proton beam radiotherapy in the pediatric population is a finding that should be evaluated. We present two cases of radiation necrosis in pediatric patients who underwent proton beam radiation therapy following gross total resection of tumors. As seen in both our cases, patients often present with radiographic changes found on surveillance imaging. While the progression of disease should certainly be considered in any patient with radiographic changes, understanding the radiographic findings and the clinical course of radiation necrosis is paramount in order to prevent unnecessary surgical intervention.

Keywords: pediatric neuro-oncology; pediatric neurosurgery; proton therapy; radiation necrosis

Conflict of interest statement

The authors have declared that no competing interests exist.

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