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Salazar-Degracia A, Busquets S, Argilés JM, et al. Formoterol attenuates increased oxidative stress and myosin protein loss in respiratory and limb muscles of cancer cachectic rats. PeerJ. 2017;5:e4109doi: 10.7717/peerj.4109.
Salazar-Degracia, A., Busquets, S., Argilés, J. M., López-Soriano, F. J., & Barreiro, E. (2017). Formoterol attenuates increased oxidative stress and myosin protein loss in respiratory and limb muscles of cancer cachectic rats. PeerJ, 5e4109. https://doi.org/10.7717/peerj.4109
Salazar-Degracia, Anna, et al. "Formoterol attenuates increased oxidative stress and myosin protein loss in respiratory and limb muscles of cancer cachectic rats." PeerJ vol. 5 (2017): e4109. doi: https://doi.org/10.7717/peerj.4109
Salazar-Degracia A, Busquets S, Argilés JM, López-Soriano FJ, Barreiro E. Formoterol attenuates increased oxidative stress and myosin protein loss in respiratory and limb muscles of cancer cachectic rats. PeerJ. 2017 Dec 13;5:e4109. doi: 10.7717/peerj.4109. eCollection 2017. PMID: 29255650; PMCID: PMC5732544.
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PeerJ. 2017 Dec 13;5:e4109. doi: 10.7717/peerj.4109. eCollection 2017.

Formoterol attenuates increased oxidative stress and myosin protein loss in respiratory and limb muscles of cancer cachectic rats.

PeerJ

Anna Salazar-Degracia, Sílvia Busquets, Josep M Argilés, Francisco J López-Soriano, Esther Barreiro

Affiliations

  1. Pulmonology Department-Muscle Wasting and Cachexia in Chronic Respiratory Diseases and Lung Cancer Research Group, Health and Experimental Sciences Department (CEXS), IMIM-Hospital del Mar, Parc de Salut Mar, Universitat Pompeu Fabra (UPF), Barcelona Biomedical Research Park (PRBB), Barcelona, Spain.
  2. Cancer Research Group, Departament de Bioquímica i Biomedicina Molecular, Facultat de Biologia, Universitat de Barcelona, Universitat de Barcelona, Barcelona, Spain.
  3. Institut de Biomedicina de la Universitat de Barcelona (IBUB), Barcelona, Spain.
  4. Centro de Investigación en Red de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III (ISCIII), Barcelona, Spain.

PMID: 29255650 PMCID: PMC5732544 DOI: 10.7717/peerj.4109

Abstract

Muscle mass loss and wasting are characteristic features of patients with chronic conditions including cancer. Therapeutic options are still scarce. We hypothesized that cachexia-induced muscle oxidative stress may be attenuated in response to treatment with beta

Keywords: Contractile proteins; Diaphragm and gastrocnemius; Experimental cancer-induced cachexia; Formoterol treatment; Redox balance

Conflict of interest statement

The authors declare there are no competing interests.

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