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Diaconu CC, Dediu GN, Iancu MA. Drug-induced arterial hypertension - a frequently ignored cause of secondary hypertension: a review. Acta Cardiol. 2018;1-7doi: 10.1080/00015385.2017.1421445.
Diaconu, C. C., Dediu, G. N., & Iancu, M. A. (2018). Drug-induced arterial hypertension - a frequently ignored cause of secondary hypertension: a review. Acta cardiologica, 1-7. https://doi.org/10.1080/00015385.2017.1421445
Diaconu, Camelia Cristina, et al. "Drug-induced arterial hypertension - a frequently ignored cause of secondary hypertension: a review." Acta cardiologica vol. (2018): 1-7. doi: https://doi.org/10.1080/00015385.2017.1421445
Diaconu CC, Dediu GN, Iancu MA. Drug-induced arterial hypertension - a frequently ignored cause of secondary hypertension: a review. Acta Cardiol. 2018 Jan 01;1-7. doi: 10.1080/00015385.2017.1421445. Epub 2018 Jan 01. PMID: 29291681.
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Acta Cardiol. 2018 Jan 01;1-7. doi: 10.1080/00015385.2017.1421445. Epub 2018 Jan 01.

Drug-induced arterial hypertension - a frequently ignored cause of secondary hypertension: a review.

Acta cardiologica

Camelia Cristina Diaconu, Giorgiana Nicoleta Dediu, Mihaela Adela Iancu

Affiliations

  1. a Internal Medicine Clinic, University of Medicine and Pharmacy "Carol Davila", Clinical Emergency Hospital of Bucharest , Romania.
  2. b Internal Medicine Clinic, University of Medicine and Pharmacy "Carol Davila", Clinical Emergency Hospital "Sf. Ioan" , Bucharest , Romania.
  3. c Department of Family Medicine , University of Medicine and Pharmacy "Carol Davila" , Bucharest , Romania.

PMID: 29291681 DOI: 10.1080/00015385.2017.1421445

Abstract

The prevalence of hypertension is likely to grow during the future years, mainly due to aging of the population and increasing prevalence of obesity, as an important risk factor for hypertension. One of the main causes of secondary hypertension, frequently ignored, is represented by certain categories of drugs, that can induce hypertension, increase the blood pressure values in previously controlled hypertension, decrease the effects of antihypertensive medication or induce a hypertensive emergency. These drugs may be over-the-counter medications, illicit drugs or prescription drugs used for the treatment of acute or chronic conditions. The most frequently incriminated drugs are steroids, nonsteroidal anti-inflammatory drugs, sympathomimetic agents, central nervous system stimulants (alcohol, amphetamine), dietary supplements (ginseng, natural liquorice etc), other therapeutic agents (sibutramine, antiemetic agents, oral physostigmine, L-dopa, leflunomide, growth hormone, thyroid hormone, recombinant human erythropoietin), antidepressants, immunosuppressants, antiangiogenic drugs, anaesthetics, heavy metals and toxins. Adding other drugs to antihypertensive treatment should be carefully evaluated by physicians, in order to avoid iatrogenic blood pressure elevations.

Keywords: Hypertension; dietary supplements; drug-induced; steroids; sympathomimetic agents

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