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Int J Biomed Imaging. 2017;2017:8318906. doi: 10.1155/2017/8318906. Epub 2017 Nov 06.

Space and Time Resolved Detection of Platelet Activation and von Willebrand Factor Conformational Changes in Deep Suspensions.

International journal of biomedical imaging

Jacopo Biasetti, Kaushik Sampath, Angel Cortez, Alaleh Azhir, Assaf A Gilad, Thomas S Kickler, Tobias Obser, Zaverio M Ruggeri, Joseph Katz

Affiliations

  1. Department of Mechanical Engineering, Johns Hopkins University, 3200 N. Charles Street, Baltimore, MD 21218, USA.
  2. Department of Radiology and Radiological Science, Johns Hopkins School of Medicine, 1550 Orleans Street, Baltimore, MD 21287, USA.
  3. Department of Biomedical Engineering, Johns Hopkins University, 3200 N. Charles Street, Baltimore, MD 21218, USA.
  4. Department of Pathology, Johns Hopkins School of Medicine, 1800 Orleans Street, Baltimore, MD 21287, USA.
  5. Department for Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, 20246 Martinistraße 52, 20251 Hamburg, Germany.
  6. MERU-Roon Research Center for Vascular Biology, Department of Molecular Medicine, The Scripps Research Institute, 10550 N. Torrey Pines Rd, La Jolla, CA 92037, USA.

PMID: 29234351 PMCID: PMC5695078 DOI: 10.1155/2017/8318906

Abstract

Tracking cells and proteins' phenotypic changes in deep suspensions is critical for the direct imaging of blood-related phenomena in

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