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Bottai V, De Paola G, Celli F, et al. Histological study of atraumatic periprosthetic fractures: does atypical periprosthetic fracture exist?. Clin Cases Miner Bone Metab. 2017;14(2):136-139doi: 10.11138/ccmbm/2017.14.1.136.
Bottai, V., De Paola, G., Celli, F., Lazzerini, I., Ortenzi, V., Naccarato, A. G., Guido, G., Capanna, R., & Giannotti, S. (2017). Histological study of atraumatic periprosthetic fractures: does atypical periprosthetic fracture exist?. Clinical cases in mineral and bone metabolism : the official journal of the Italian Society of Osteoporosis, Mineral Metabolism, and Skeletal Diseases, 14(2), 136-139. https://doi.org/10.11138/ccmbm/2017.14.1.136
Bottai, Vanna, et al. "Histological study of atraumatic periprosthetic fractures: does atypical periprosthetic fracture exist?." Clinical cases in mineral and bone metabolism : the official journal of the Italian Society of Osteoporosis, Mineral Metabolism, and Skeletal Diseases vol. 14,2 (2017): 136-139. doi: https://doi.org/10.11138/ccmbm/2017.14.1.136
Bottai V, De Paola G, Celli F, Lazzerini I, Ortenzi V, Naccarato AG, Guido G, Capanna R, Giannotti S. Histological study of atraumatic periprosthetic fractures: does atypical periprosthetic fracture exist?. Clin Cases Miner Bone Metab. 2017 May-Aug;14(2):136-139. doi: 10.11138/ccmbm/2017.14.1.136. Epub 2017 Oct 25. PMID: 29263721; PMCID: PMC5726197.
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Clin Cases Miner Bone Metab. 2017 May-Aug;14(2):136-139. doi: 10.11138/ccmbm/2017.14.1.136. Epub 2017 Oct 25.

Histological study of atraumatic periprosthetic fractures: does atypical periprosthetic fracture exist?.

Clinical cases in mineral and bone metabolism : the official journal of the Italian Society of Osteoporosis, Mineral Metabolism, and Skeletal Diseases

Vanna Bottai, Gaia De Paola, Fabio Celli, Ilaria Lazzerini, Valerio Ortenzi, Antonio Giuseppe Naccarato, Giulio Guido, Rodolfo Capanna, Stefano Giannotti

Affiliations

  1. II Orthopaedic and Traumatologic Clinic, University of Pisa, Pisa, Italy.
  2. Division of Surgical, Molecular and Ultrastructural Pathology, University of Pisa, Pisa, Italy.
  3. Ortopedic Clinic, University of Siena, Siena, Italy.

PMID: 29263721 PMCID: PMC5726197 DOI: 10.11138/ccmbm/2017.14.1.136

Abstract

PURPOSE: Is it possible a correlation between some periprosthetic femoral fractures and atypical fractures?

CASE: We present a case of a 77-year-old woman with atypical periprosthetic femoral fracture. The patient had a history of long-term bisphosphonate use. We performed an open reduction, a synthesis of the fracture and a histological exam. The patient stopped the bisphosphonate (BF) therapy. Three months later, before starting the teriparatide treatment, the patient had a re-fracture so we did a second osteosynthesis and began a teriparatide therapy. After six months, the radiography showed a bone healing at the fracture site.

RESULT: The histological examination confirmed the diagnosis of atypical femoral fracture.

CONCLUSION: At first, the fracture showed a delayed union which led to a new surgery, as often happens in BF-related atypical fractures. Appropriate treatment (BF suspension and teriparatide beginning) permitted fracture healing. The atypical characteristic of the fracture was confirmed by histological exam.Some periprosthetic femoral fractures in patients treated with BF, especially in long time therapies, should be suspected as atypical fractures and a specific medical treatment should be performed, as well as a correct surgical treatment.

Keywords: atypical fracture; bisphosphonate; fracture healing; hip replacement; periprosthetic fracture

Conflict of interest statement

Disclosure The Authors declare no conflict of interest. No financial support was received for this study. Written informed consent was obtained from the patient for publication of this case report and

References

  1. Bone Joint J. 2014 May;96-B(5):658-64 - PubMed
  2. Eur J Orthop Surg Traumatol. 2013 Nov;23 Suppl 2:S291-4 - PubMed
  3. J Orthop Res. 2015 Apr;33(4):504-12 - PubMed
  4. J Bone Miner Res. 2014 Jan;29(1):1-23 - PubMed
  5. Orthopedics. 2011 Dec 06;34(12 ):e939-44 - PubMed
  6. Clin Cases Miner Bone Metab. 2013 May;10(2):116-20 - PubMed
  7. Acta Orthop Suppl. 2013 Dec;84(352):1-26 - PubMed
  8. Clin Cases Miner Bone Metab. 2015 Sep-Dec;12(3):247-50 - PubMed
  9. F1000Res. 2014 Jun 17;2:266 - PubMed
  10. J Bone Joint Surg Br. 2012 Jul;94(7):994-7 - PubMed
  11. Acta Orthop. 2015;86(5):622-6 - PubMed
  12. Acta Orthop. 2014 Jun;85(3):280-6 - PubMed
  13. Case Rep Surg. 2014;2014:631709 - PubMed
  14. Osteoporos Int. 2014 Mar;25(3):993-7 - PubMed
  15. Osteoporos Int. 2013 Nov;24(11):2893-5 - PubMed

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