Display options
Cite
Flais J, Coiffier G, Brillet E, et al. Atypical presentation of spine bone metastasis in prostate cancer mimicking Pott's disease. Clin Cases Miner Bone Metab. 2017;14(2):239-240doi: 10.11138/ccmbm/2017.14.1.239.
Flais, J., Coiffier, G., Brillet, E., Perdriger, A., & Guggenbuhl, P. (2017). Atypical presentation of spine bone metastasis in prostate cancer mimicking Pott's disease. Clinical cases in mineral and bone metabolism : the official journal of the Italian Society of Osteoporosis, Mineral Metabolism, and Skeletal Diseases, 14(2), 239-240. https://doi.org/10.11138/ccmbm/2017.14.1.239
Flais, Jérémy, et al. "Atypical presentation of spine bone metastasis in prostate cancer mimicking Pott's disease." Clinical cases in mineral and bone metabolism : the official journal of the Italian Society of Osteoporosis, Mineral Metabolism, and Skeletal Diseases vol. 14,2 (2017): 239-240. doi: https://doi.org/10.11138/ccmbm/2017.14.1.239
Flais J, Coiffier G, Brillet E, Perdriger A, Guggenbuhl P. Atypical presentation of spine bone metastasis in prostate cancer mimicking Pott's disease. Clin Cases Miner Bone Metab. 2017 May-Aug;14(2):239-240. doi: 10.11138/ccmbm/2017.14.1.239. Epub 2017 Oct 25. PMID: 29263741; PMCID: PMC5726217.
Copy Download .nbib Format: NLM
Share it on

Clin Cases Miner Bone Metab. 2017 May-Aug;14(2):239-240. doi: 10.11138/ccmbm/2017.14.1.239. Epub 2017 Oct 25.

Atypical presentation of spine bone metastasis in prostate cancer mimicking Pott's disease.

Clinical cases in mineral and bone metabolism : the official journal of the Italian Society of Osteoporosis, Mineral Metabolism, and Skeletal Diseases

Jérémy Flais, Guillaume Coiffier, Eric Brillet, Aleth Perdriger, Pascal Guggenbuhl

Affiliations

  1. CHU Rennes, Service de Rhumatologie, Rennes, France.
  2. Universite Rennes 1, Faculte de Medecine, Rennes, France.
  3. CHU Rennes, Service d'Imagerie Medicale, Unite Musculo-Squelettique, Rennes, France.
  4. INSERM UMR 991, Rennes, France.

PMID: 29263741 PMCID: PMC5726217 DOI: 10.11138/ccmbm/2017.14.1.239

Abstract

A 55-year-old man was hospitalized for a low back pain lasting for 3 months. Spinal MRI revealed a suggestive aspect of multilevel discitis L5-S1-S2 with paravertebral abscess. A thoraco-abdominal CT scan confirmed the presence of multiple pathological lymph nodes in several locations, bilateral micronodular pulmonary infiltrate; it also showed mirror bone erosions of vertebral L5 and S1 endplates, suggestive of disseminated tuberculosis with lung involvement and lymphadenopathy. A discovertebral L5-S1 biopsy was performed confirming the diagnosis of metastatic prostatic adenocarcinoma including a tumor infiltration of the intervertebral disc, without arguments for a septic processus superimposed without tuberculosis granuloma. Although rare, cases of metastases located at the disco-vertebral junction including prostatic cancer have already been described, and should be known to the clinician. The differential diagnosis with an infectious spondylodiscitis can be difficult in some case around the vertebral disc and in case of epiduritis and soft tissues involvement on MRI sequences. Disco-vertebral biopsy remains the cornerstone of the diagnosis.

Keywords: metastasis; prostate cancer; spondylodiscitis; tuberculosis

Conflict of interest statement

Conflicts of interests The Authors declare that they have no conflicts of interest related to this article.

References

  1. Clin Orthop Relat Res. 2002 May;(398):32-9 - PubMed
  2. Joint Bone Spine. 2009 Jan;76(1):50-6 - PubMed
  3. Invest Radiol. 1978 May-Jun;13(3):182-90 - PubMed
  4. Neuroradiology. 1996 May;38 Suppl 1:S97-104 - PubMed

Publication Types