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Ann Maxillofac Surg. 2017 Jul-Dec;7(2):278-281. doi: 10.4103/ams.ams_86_17.

Post Herpetic Frey's Syndrome.

Annals of maxillofacial surgery

Jigna S Shah, Vijay K Asrani

Affiliations

  1. Department of Oral Medicine and Radiology, Government Dental College and Hospital, Ahmedabad, Gujarat, India.

PMID: 29264298 PMCID: PMC5717907 DOI: 10.4103/ams.ams_86_17

Abstract

Frey's syndrome is characterized by unilateral sweating and flushing of the skin in the area of the parotid gland, occurring during meal, or on salivary stimulation. It is a common complication following surgery/injury in the parotid gland region/temporomandibular joint surgery; however, very few cases have been reported of its occurrence following herpetic infection. It is important for the clinician to recognize its unusual symptoms as early as possible to prevent its potential negative social and psychological effect on the patient. It is diagnosed on clinical presentation and confirmed by objective testing methods. The treatment ranges from topical application of glycopyrrolate to local injections of botulinum toxin and lastly to surgical intervention. An interesting case of Frey's syndrome is presented in a young patient having the previous history of herpes zoster infection, which was diagnosed clinically and confirmed by starch-iodine test and was successfully treated with topical application of glycopyrrolate.

Keywords: Frey's syndrome; glycopyrrolate; herpes infection; minor-starch iodine test

Conflict of interest statement

There are no conflicts of interest.

References

  1. J Oral Maxillofac Surg. 2000 Dec;58(12):1411-4 - PubMed
  2. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2002 Sep;94(3):338-40 - PubMed
  3. Clin Exp Dermatol. 1998 Sep;23(5):204-5 - PubMed
  4. Pediatr Dermatol. 2000 Mar-Apr;17(2):126-8 - PubMed
  5. Ann Neurol. 1987 Jun;21(6):559-63 - PubMed
  6. Braz Dent J. 2004;15(2):159-62 - PubMed
  7. Clin Otolaryngol Allied Sci. 1998 Aug;23(4):291-301 - PubMed
  8. Br J Surg. 2002 Jan;89(1):116-9 - PubMed
  9. J Oral Maxillofac Surg. 2004 Jul;62(7):840-4 - PubMed

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