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Shokri A, Saeedi M, Fakhar M, et al. Antileishmanial Activity of . Iran J Parasitol. 2017;12(4):622-631
Shokri, A., Saeedi, M., Fakhar, M., Morteza-Semnani, K., Keighobadi, M., Hosseini Teshnizi, S., Kelidari, H. R., & Sadjadi, S. (2017). Antileishmanial Activity of . Iranian journal of parasitology, 12(4), 622-631.
Shokri, Azar, et al. "Antileishmanial Activity of ." Iranian journal of parasitology vol. 12,4 (2017): 622-631.
Shokri A, Saeedi M, Fakhar M, Morteza-Semnani K, Keighobadi M, Hosseini Teshnizi S, Kelidari HR, Sadjadi S. Antileishmanial Activity of . Iran J Parasitol. 2017 Oct-Dec;12(4):622-631. PMID: 29317888; PMCID: PMC5756313.
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Iran J Parasitol. 2017 Oct-Dec;12(4):622-631.

Antileishmanial Activity of .

Iranian journal of parasitology

Azar Shokri, Majid Saeedi, Mahdi Fakhar, Katayoun Morteza-Semnani, Masoud Keighobadi, Saeed Hosseini Teshnizi, Hamid Reza Kelidari, Siamak Sadjadi

Affiliations

  1. Students Research Committee, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
  2. Molecular and Cell Biology Research Center, Dept. of Parasitology, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
  3. Dept. of Pharmaceutics, School of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran.
  4. Dept. of Medicinal Chemistry, School of Pharmacy, Mazandaran University of Medical, Sciences, Sari, Iran.
  5. Students Research Committee, School of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran.
  6. Infectious and Tropical Diseases Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.

PMID: 29317888 PMCID: PMC5756313

Abstract

BACKGROUND: The aim of present study was to evaluate antileishmanial effects of

METHODS: The present study was performed in Leishmaniasis Reference Lab at Mazandaran University of Medical Sciences, Iran during 2016-2017. The IC50 values were calculated in both the promastigote and amastigote stages in J774 macrophage in comparison with meglumine antimoniate (MA) as positive control. In addition, cytotoxicity effects of essential oils and nano-emulsions prepared from both plants against macrophages were evaluated.

RESULTS: Both essential oil and nano-emulsion of

CONCLUSION: The nano-emulsions of both plants were more effective than essential oil in both MIR and amastigote. However, in comparison with MA, the

Keywords: Essential oil; Lavandula angustifolia; Leishmania major; Nano-emulsion; Rosmarinus officinalis

Conflict of interest statement

Conflict of interest The authors declare that have no conflict of interests.

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