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Bally A, Acevedo KF, Pargass I, et al. A Multicentric T-Cell Lymphoma with a Plasmacytoid Morphology in a Dog. Vet Sci. 2018;5(1)doi: 10.3390/vetsci5010010.
Bally, A., Acevedo, K. F., Pargass, I., Gyan, L., Rajh, S., & Suepaul, R. (2018). A Multicentric T-Cell Lymphoma with a Plasmacytoid Morphology in a Dog. Veterinary sciences, 5(1), . https://doi.org/10.3390/vetsci5010010
Bally, Alissa, et al. "A Multicentric T-Cell Lymphoma with a Plasmacytoid Morphology in a Dog." Veterinary sciences vol. 5,1 (2018). doi: https://doi.org/10.3390/vetsci5010010
Bally A, Acevedo KF, Pargass I, Gyan L, Rajh S, Suepaul R. A Multicentric T-Cell Lymphoma with a Plasmacytoid Morphology in a Dog. Vet Sci. 2018 Jan 20;5(1). doi: 10.3390/vetsci5010010. PMID: 29361706; PMCID: PMC5876584.
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Vet Sci. 2018 Jan 20;5(1). doi: 10.3390/vetsci5010010.

A Multicentric T-Cell Lymphoma with a Plasmacytoid Morphology in a Dog.

Veterinary sciences

Alissa Bally, Karelma Frontera Acevedo, Indira Pargass, Lana Gyan, Stacy Rajh, Rod Suepaul

Affiliations

  1. The School of Veterinary Medicine, University of the West Indies, Saint Augustine, Trinidad and Tobago. [email protected].
  2. The School of Veterinary Medicine, University of the West Indies, Saint Augustine, Trinidad and Tobago. [email protected].
  3. The School of Veterinary Medicine, University of the West Indies, Saint Augustine, Trinidad and Tobago. [email protected].
  4. Veterinary Diagnostic Laboratory, Ministry of Agriculture, Land and Fisheries, Eric Williams Medical Sciences Complex, Uriah Butler Highway, Mt Hope, Trinidad and Tobago. [email protected].
  5. The School of Veterinary Medicine, University of the West Indies, Saint Augustine, Trinidad and Tobago. [email protected].
  6. The School of Veterinary Medicine, University of the West Indies, Saint Augustine, Trinidad and Tobago. [email protected].

PMID: 29361706 PMCID: PMC5876584 DOI: 10.3390/vetsci5010010

Abstract

An 8-year-old male (neutered) Labrador with a history of erythematous skin lesions and exercise intolerance for a prolonged period was suddenly found dead. Necropsy findings revealed an infiltrative, focally extensive mass which occupied 25% of the cardiac interventricular septum. Severe endocardiosis was also found on the bicuspid and tricuspid valves. The submandibular lymph nodes and kidneys were bilaterally enlarged, and the pre-hepatic lymph node and spleen were also enlarged. Multiple dermal pustules were present around the mouth and on the ear, and small ulcers were present on the tongue. Histopathological examination detected the presence of neoplastic lymphocytes with a plasmacytoid morphology in these tissues as well as in the tongue and skin lesions. Immunohistochemical (CD3⁺/CD18⁺) evaluation was consistent with a T-cell lymphoma, which could be classified as a peripheral T-cell lymphoma, not otherwise specified (PTCL-NOS).

Keywords: T-cell lymphoma; canine; immunohistochemistry; multicentric; pathology; plasmacytoid morphology

Conflict of interest statement

The authors declare no conflict of interest.

References

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