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Gig Sanit. 2016;95(8):743-8.

[Risk assessment from exposure to chemical contaminants in food].

Gigiena i sanitariia

[Article in Russian]
O A Frolova, E P Bocharov, L A Akhtyamova

PMID: 29430899

Abstract

There was investigated the impact of chemical substances contained in the public health foodstuffs in eight regions of the Republic of Tatarstan on 11 product groups: meat and meat products, fish and fish products, milk and dairy products, bread and bakery products, sugar and confectionery products, vegetables and melons (excluding potatoes), potatoes, fruits and berries, vegetable oil, eggs and egg products, salt. In total there were analyzed more than 240 thousand samples offood raw materials andfood products over the period offrom 2006 to 2014. The study took place on 27 priority chemicals, including thirteen carcinogens (benzo (a) pyrene, DDT, hexachlorobenzene, hexachloran, heptachlor, alpha-lindane, beta-lindane, lindane, cadmium, arsenic, lead, derivatives of 2,4-D acid, cypermethrin). Exposition load is calculated by the 50 (median), and 90 percentiles of the content ofpollutants in food products. There were calculated carcinogenic risks, HQ coefficients and HI indices for chronic non-cancer exposure. High values of the total cancer risk (3.31*10 at the median level of 1.49*10+ at the 90 percentile) are associated with the exposure to tohexachlorane and alpha-lindane seem to be alarming (from 1.73*10 to 9.68*10) with the effect of lindane, cadmium and lead with dominant contribution to the total risk in the use of meat and meat products, milk and dairy products. The warning value of Hazard ratios (HQ 1.1-3) at 90-percentile were shown on nitrate, lead, beta-lindane, high (HQ >3), for DDT and its metabolites, lindane and arsenic, with the dominant contribution to the exposure of vegetables and melons (excluding potatoes), potato, milk and milk products.

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